Vaccination of cats against feline immunodeficiency virus (FIV): a matter of challenge

被引：13

作者：

Hesselink, W ^{[1
]}

Sondermeijer, P ^{[1
]}

Pouwels, H ^{[1
]}

Verblakt, E ^{[1
]}

Dhore, C ^{[1
]}

机构：

[1] Intervet Int BV, NL-5830 AA Boxmeer, Netherlands

来源：

VETERINARY MICROBIOLOGY | 1999年 / 69卷 / 1-2期

关键词：

cat; virology; vaccine; feline immunodeficiency virus; AIDS;

D O I：

10.1016/S0378-1135(99)00096-6

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

So far, most apparently successful immunodeficiency virus vaccines have only been tested against challenge with cell culture-adapted virus. However, even live priming of cats with feline herpesvirus (FHV) vectors expressing the FIV gag and env gene followed by inactivated booster vaccination with fixed FIX infected cell vaccine proved non-protective against infection with a primary FIV isolate. An effective FN vaccine for field applications therefore is still not underway. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：109 / 110

页数：2