Renal Failure in Patients with Left Ventricular Assist Devices

被引：71

作者：

Patel, Ami M. ^{[1
]}

Adeseun, Gbemisola A. ^{[2
]}

Ahmed, Irfan ^{[1
]}

Mitter, Nanhi ^{[3
]}

Rame, J. Eduardo ^{[4
]}

Rudnick, Michael R. ^{[5
]}

机构：

[1] Drexel Univ, Coll Med, Dept Med, Div Nephrol, Philadelphia, PA 19102 USA

[2] Univ So Calif, Keck Sch Med, Div Nephrol, Los Angeles, CA 90033 USA

[3] Johns Hopkins Univ, Sch Med, Dept Anesthesiol & Crit Care Med, Baltimore, MD 21205 USA

[4] Univ Penn, Dept Med, Div Cardiol, Philadelphia, PA 19104 USA

[5] Univ Penn, Dept Med, Div Renal Electrolyte & Hypertens, Philadelphia, PA 19104 USA

来源：

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY | 2013年 / 8卷 / 03期

关键词：

MECHANICAL CIRCULATORY SUPPORT; ADVANCED HEART-FAILURE; END-ORGAN FUNCTION; RENIN-ANGIOTENSIN SYSTEM; INTERMACS ANNUAL-REPORT; CONTINUOUS BLOOD-FLOW; DESTINATION THERAPY; CARDIOGENIC-SHOCK; CARDIAC-SUPPORT; CLINICAL-EXPERIENCE;

D O I：

10.2215/CJN.06210612

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Implantable left ventricular assist devices (LVADs) are increasingly being used as a bridge to transplantation or as destination therapy in patients with end stage heart failure refractory to conventional medical therapy. A significant number of these patients have associated renal dysfunction before LVAD implantation, which may improve after LVAD placement due to enhanced perfusion. Other patients develop AKI after implantation. LVAD recipients who develop AKI requiring renal replacement therapy in the hospital or who ultimately require long-term outpatient hemodialysis therapy present management challenges with respect to hemodynamics, volume, and dialysis access. This review discusses the mechanics of a continuous-flow LVAD (the HeartMate II), the effects of continuous blood flow on the kidney, renal outcomes of patients after LVAD implantation, dialysis modality selection, vascular access, hemodynamic monitoring during the dialytic procedure, and other issues relevant to caring for these patients. Clin J Am Soc Nephrol 8: 484-496, 2013. doi: 10.2215/CJN.06210612

引用

页码：484 / 496

页数：13

共 82 条

[1] Patient selection for left ventricular assist device therapy [J].

Aaronson, KD ;

Patel, H ;

Pagani, FD .

ANNALS OF THORACIC SURGERY, 2003, 75 (06) :S29-S35

[2]

Alba Ana C, 2009, J Card Fail, V15, P874, DOI 10.1016/j.cardfail.2009.05.015

[3] Peripheral vascular reactivity in patients with pulsatile vs axial flow left ventricular assist device support [J].

Amir, O ;

Radovancevic, B ;

Delgado, RM ;

Kar, B ;

Radovancevic, R ;

Henderson, M ;

Cohn, WE ;

Smart, FW .

JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2006, 25 (04) :391-394

[4]

[Anonymous], 2008, HEARTMATE 2 LVAS CLI

[5]

[Anonymous], 2012, HEARTMATE 2 LVAS OP

[6] Effects of left ventricular assist devices on outcomes in patients undergoing heart transplantation [J].

Bank, AJ ;

Mir, SH ;

Nguyen, DQ ;

Bolman, RM ;

Shumway, SJ ;

Miller, LW ;

Kaiser, DR ;

Ormaza, SM ;

Park, SJ .

ANNALS OF THORACIC SURGERY, 2000, 69 (05) :1369-1374

[7] IMPROVED MULTIORGAN FUNCTION AFTER PROLONGED UNIVENTRICULAR SUPPORT [J].

BURNETT, CM ;

DUNCAN, JM ;

FRAZIER, OH ;

SWEENEY, MS ;

VEGA, JD ;

RADOVANCEVIC, B .

ANNALS OF THORACIC SURGERY, 1993, 55 (01) :65-71

[8] Relationship between renal function and left ventricular assist device use [J].

Butler, J ;

Geisberg, C ;

Howser, R ;

Portner, PM ;

Rogers, JG ;

Deng, MC ;

Pierson, RN .

ANNALS OF THORACIC SURGERY, 2006, 81 (05) :1745-1751

[9] Renal function after orthotopic liver transplantation is predicted by duration of pretransplantation creatinine elevation [J].

Campbell, MS ;

Kotlyar, DS ;

Brensinger, CM ;

Lewis, JD ;

Shetty, K ;

Bloom, RD ;

Markmann, JF ;

Olthoff, KM ;

Shaked, A ;

Reddy, KR .

LIVER TRANSPLANTATION, 2005, 11 (09) :1048-1055

[10] Past, Present, and Future of Long-Term Mechanical Cardiac Support in Adults [J].

Christiansen, Stefan ;

Klocke, Anna ;

Autschbach, Ruediger .

JOURNAL OF CARDIAC SURGERY, 2008, 23 (06) :664-676

← 1 2 3 4 5 6 7 8 9 →