Adiponectin: A biomarker for chronic hepatitis C?

被引：7

作者：

Liu, Ding ^{[1
]}

Li, Shengyu ^{[2
]}

Li, Zhihong ^{[1
]}

机构：

[1] Cent S Univ, Xiangya Hosp 2, Dept Orthopaed, Changsha, Hunan, Peoples R China

[2] Cent S Univ, Xiangya Hosp, Dept Gen Surg, Changsha, Hunan, Peoples R China

来源：

CYTOKINE | 2017年 / 89卷

基金：

中国国家自然科学基金;

关键词：

Adiponectin; Chronic hepatitis C; Biomarker; NECROSIS-FACTOR-ALPHA; INSULIN-RESISTANCE; PLASMA ADIPONECTIN; METABOLIC SYNDROME; T-CADHERIN; HEPATOCELLULAR-CARCINOMA; FIBROSIS PROGRESSION; SERUM ADIPONECTIN; ADIPOSE-TISSUE; NONALCOHOLIC STEATOHEPATITIS;

D O I：

10.1016/j.cyto.2015.10.016

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Adiponectin, a hormone primarily synthesized and secreted by adipose tissue, plays a pivotal role in lipid metabolism. Chronic hepatitis C (CHC) infection is characterized by disordered lipid metabolism, which may potentially evolve into steatosis over a period of time. A growing body of evidence appears to link decreased adiponectin plasma levels with severe CHC-related steatosis, which suggests a potential role of this adipokine as a diagnostic and therapeutic target for clinical application. In this review, we have attempted to summarize the current status of adiponectin research in the context of CHC, concentrating predominantly on its roles in CHC, and its potential relevance as a biomarker for CHC. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：27 / 33

页数：7

共 50 条

[21] Circulating microRNA-196a as a candidate diagnostic biomarker for chronic hepatitis C
Liu, Bo
Xiang, Ying
Zhang, Heng-Shu
MOLECULAR MEDICINE REPORTS, 2015, 12 (01) : 105 - 110
[22] Increased circulating adiponectin in males with chronic HCV hepatitis
Canavesi, Elena
Porzio, Marianna
Ruscica, Massimiliano
Rametta, Raffaela
Macchi, Chiara
Pelusi, Serena
Fracanzani, Anna Ludovica
Dongiovanni, Paola
Fargion, Silvia
Magni, Paolo
Valenti, Luca
EUROPEAN JOURNAL OF INTERNAL MEDICINE, 2015, 26 (08) : 635 - 639
[23] Adiponectin and its receptors in patients with chronic hepatitis B
Zhang, J. Q.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2010, 14 : S55 - S55
[24] The Relationship Between Serum Adiponectin and Steatosis in Patients with Chronic Hepatitis C Genotype-4
Ashour, Esmat
Samy, Nervana
Sayed, Magda
Imam, Azza
CLINICAL LABORATORY, 2010, 56 (3-4) : 103 - 110
[25] Chronic hepatitis B and chronic hepatitis C
不详
AMERICAN FAMILY PHYSICIAN, 1996, 54 (05) : 1603 - 1605
[26] Diagnostic value of multiple biomarker panel for prediction of significant fibrosis in chronic hepatitis C
Park, Seung Ha
Kim, Chang Hoon
Kim, Dong Joon
Suk, Ki Tae
Park, Jong Ha
Cheong, Jae Youn
Cho, Sung Won
Hwang, Seong Gyu
Lee, Youn Jae
Cho, Mong
Yang, Jin Mo
Park, Ha Young
Kim, Young Bae
CLINICAL BIOCHEMISTRY, 2011, 44 (17-18) : 1396 - 1399
[27] Circulating miRNAs as biomarker for liver fibrosis in chronic hepatitis B and C virus infection
Lambrecht, Joeri
Poortmans, Pieter Jan
Reynaert, Hendrik
van Grunsven, Leo A.
ACTA CLINICA BELGICA, 2016, 71 : 9 - 9
[28] Adiponectin: A New Independent Predictor of Liver Steatosis and Response to IFN-α Treatment in Chronic Hepatitis C
Zografos, Theodoros A.
Liaskos, Christos
Rigopoulou, Eirini I.
Togousidis, Elias
Makaritsis, Kostantinos
Germenis, Anastasios
Dalekos, George N.
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2008, 103 (03): : 605 - 614
[29] Adiponectin: A new independent predictor of liver steatosis and response to IFN-A treatment in chronic hepatitis C?
Zagrafos, Theodoros A.
Liaskos, Christos
Rigopoulou, Eirini I.
Togousidis, Elias
Makaritsis, Kostantinos
Germenis, Anastasios
Dalekos, George N.
HEPATOLOGY, 2007, 46 (04) : 449A - 450A
[30] High molecular weight form of adiponectin levels of Japanese patients with chronic hepatitis C virus infection
Furusyo, Norihiro
Sawayama, Yasunori
Maeda, Shinji
Toyoda, Kazuhiro
Takeoka, Hiroaki
Murata, Masayuki
Ohnishi, Hachiro
Hayashi, Jun
HEPATOLOGY RESEARCH, 2007, 37 (12) : 1052 - 1061

← 1 2 3 4 5 →