The lbp gene, which encodes a laminin-binding protein (Lbp) of Streptococcus pyogenes, was found in all S. pyogenes M types. An Lbp-deficient mutant showed a significant, lower efficiency of adhesion to HEp-2 cells than did the wild-type strain. These results indicate that Lbp is one of the important S. pyogenes adhesins.
机构:
GBF, Natl Res Ctr Biotechnol, Div Microbiol, D-38124 Braunschweig, GermanyGBF, Natl Res Ctr Biotechnol, Div Microbiol, D-38124 Braunschweig, Germany
Molinari, G
Chhatwal, GS
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机构:
GBF, Natl Res Ctr Biotechnol, Div Microbiol, D-38124 Braunschweig, GermanyGBF, Natl Res Ctr Biotechnol, Div Microbiol, D-38124 Braunschweig, Germany