Effect of heat stress on HSP70 gene expression pattern in different vital organs of Malabari goats

The study was conducted to establish the impact of heat stress on the expression pattern of heat shock protein 70 (HSP70) gene in different organs of Malabari goats. The study was conducted for a period of 45 days and the animals were allocated into two groups: MC (n = 6; Malabari control) and MHS (n = 6; Malabari heat stress). Heat stress significantly increased the HSP70 expression pattern in adrenal while significantly lowered the HSP70 expression pattern in thyroid and mesenteric lymph node. However, heat stress did not influence the expression pattern of HSP70 gene in both liver and uterus. Further, a strong positive correlation was established between temperature-humidity-index (THI) and HSP70 gene expression in liver and uterus while negative correlation with HSP70 gene expression in thyroid and LN. Thus, it can be concluded that the expression pattern of HSP70 gene was tissue and function specific and it was programmed according to the requirement of the heat stressed animals of Malabari goats.