Progressive Multiscale Consistent Network for Multiclass Fundus Lesion Segmentation

被引:34
作者
He, Along [1 ]
Wang, Kai [1 ]
Li, Tao [2 ]
Bo, Wang [1 ]
Kang, Hong [1 ]
Fu, Huazhu [3 ]
机构
[1] Nankai Univ, Coll Comp Sci, Tianjin Key Lab Network & Data Secur Technol, Tianjin 300350, Peoples R China
[2] Nankai Univ, Coll Comp Sci, Natl & Local Joint Engn Res Ctr Biomass Resource, Tianjin 300350, Peoples R China
[3] ASTAR, Inst High Performance Comp IHPC, Singapore 138632, Singapore
关键词
Lesions; Image segmentation; Feature extraction; Task analysis; Optical imaging; Biomedical optical imaging; Semantics; Multi-class segmentation; multi-scale fundus lesions; progressive feature fusion; dynamic attention block; consistent multi-scale; EXUDATE;
D O I
10.1109/TMI.2022.3177803
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
Effectively integrating multi-scale information is of considerable significance for the challenging multi-class segmentation of fundus lesions because different lesions vary significantly in scales and shapes. Several methods have been proposed to successfully handle the multi-scale object segmentation. However, two issues are not considered in previous studies. The first is the lack of interaction between adjacent feature levels, and this will lead to the deviation of high-level features from low-level features and the loss of detailed cues. The second is the conflict between the low-level and high-level features, this occurs because they learn different scales of features, thereby confusing the model and decreasing the accuracy of the final prediction. In this paper, we propose a progressive multi-scale consistent network (PMCNet) that integrates the proposed progressive feature fusion (PFF) block and dynamic attention block (DAB) to address the aforementioned issues. Specifically, PFF block progressively integrates multi-scale features from adjacent encoding layers, facilitating feature learning of each layer by aggregating fine-grained details and high-level semantics. As features at different scales should be consistent, DAB is designed to dynamically learn the attentive cues from the fused features at different scales, thus aiming to smooth the essential conflicts existing in multi-scale features. The two proposed PFF and DAB blocks can be integrated with the off-the-shelf backbone networks to address the two issues of multi-scale and feature inconsistency in the multi-class segmentation of fundus lesions, which will produce better feature representation in the feature space. Experimental results on three public datasets indicate that the proposed method is more effective than recent state-of-the-art methods.
引用
收藏
页码:3146 / 3157
页数:12
相关论文
共 48 条
[1]  
[Anonymous], 2009, GLOBAL HEALTH RISKS: MORTALITY AND BURDEN OF DISEASE ATTRIBUTABLE TO SELECTED MAJOR RISKS, P1
[2]  
Chen LC, 2017, Arxiv, DOI [arXiv:1706.05587, DOI 10.48550/ARXIV.1706.05587]
[3]   Encoder-Decoder with Atrous Separable Convolution for Semantic Image Segmentation [J].
Chen, Liang-Chieh ;
Zhu, Yukun ;
Papandreou, George ;
Schroff, Florian ;
Adam, Hartwig .
COMPUTER VISION - ECCV 2018, PT VII, 2018, 11211 :833-851
[4]   DeepLab: Semantic Image Segmentation with Deep Convolutional Nets, Atrous Convolution, and Fully Connected CRFs [J].
Chen, Liang-Chieh ;
Papandreou, George ;
Kokkinos, Iasonas ;
Murphy, Kevin ;
Yuille, Alan L. .
IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE, 2018, 40 (04) :834-848
[5]   IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045 [J].
Cho, N. H. ;
Shaw, J. E. ;
Karuranga, S. ;
Huang, Y. ;
Fernandes, J. D. da Rocha ;
Ohlrogge, A. W. ;
Malanda, B. .
DIABETES RESEARCH AND CLINICAL PRACTICE, 2018, 138 :271-281
[6]   Microaneurysm detection using fully convolutional neural networks [J].
Chudzik, Piotr ;
Majumdar, Somshubra ;
Caliva, Francesco ;
Al-Diri, Bashir ;
Hunter, Andrew .
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE, 2018, 158 :185-192
[7]   Clinical Report Guided Retinal Microaneurysm Detection With Multi-Sieving Deep Learning [J].
Dai, Ling ;
Fang, Ruogu ;
Li, Huating ;
Hou, Xuhong ;
Sheng, Bin ;
Wu, Qiang ;
Jia, Weiping .
IEEE TRANSACTIONS ON MEDICAL IMAGING, 2018, 37 (05) :1149-1161
[8]   TeleOphta: Machine learning and image processing methods for teleophthalmology [J].
Decenciere, E. ;
Cazuguel, G. ;
Zhang, X. ;
Thibault, G. ;
Klein, J. -C. ;
Meyer, F. ;
Marcotegui, B. ;
Quellec, G. ;
Lamard, M. ;
Danno, R. ;
Elie, D. ;
Massin, P. ;
Viktor, Z. ;
Erginay, A. ;
Lay, B. ;
Chabouis, A. .
IRBM, 2013, 34 (02) :196-203
[9]   Deep Retinal Image Segmentation: A FCN-Based Architecture with Short and Long Skip Connections for Retinal Image Segmentation [J].
Feng, Zhongwei ;
Yang, Jie ;
Yao, Lixiu ;
Qiao, Yu ;
Yu, Qi ;
Xu, Xun .
NEURAL INFORMATION PROCESSING (ICONIP 2017), PT IV, 2017, 10637 :713-722
[10]   Joint Optic Disc and Cup Segmentation Based on Multi-Label Deep Network and Polar Transformation [J].
Fu, Huazhu ;
Cheng, Jun ;
Xu, Yanwu ;
Wong, Damon Wing Kee ;
Liu, Jiang ;
Cao, Xiaochun .
IEEE TRANSACTIONS ON MEDICAL IMAGING, 2018, 37 (07) :1597-1605