Antitumor activity of some novel 1,2,5-thiadiazole derivatives

被引：19
作者：
Ismail, Z. H. [2 ]
Ghorab, M. M. [3 ]
Mohamed, E. M. A. [2 ]
Aly, H. M. [2 ]
El-Gaby, M. S. A. [1 ]
机构：
[1] Al Azhar Univ, Fac Sci, Dept Chem, Assiut 71524, Egypt
[2] Al Azhar Univ, Fac Sci Girls, Dept Chem, Cairo, Egypt
[3] Natl Ctr Radiat Res & Technol, Dept Drug Radiat Res, Nasr City, Cairo, Egypt
来源：
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2008年 / 183卷 / 10期
关键词：
1,2,5-thiadiazole; antitumor activity; pyrazole; quinazoline derivatives; thiourea;
D O I：
10.1080/10426500801967815
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Some novel thiourea,1,2,4-triazole, quinazoline, thieno[2,3-d]pyrimi-dine, and thiazolidine derivatives were synthesized to evaluate their antitumor activity. Compound (3f) is nearly as active as reference drug, (Doxorubicin) as positive control.
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收藏
页码：2541 / 2554
页数：14
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