A facile synthesis of novel benzofuran-2-yl(9-methyl-9H-carbazol-3-yl)methanones

被引：4
|
作者：
Zhang, Hong [1 ]
Yan, Yan [1 ]
Li, Yang [1 ]
Gao, Wentao [1 ]
机构：
[1] Bohai Univ, Inst Superfine Chem, Jinzhou 121000, Peoples R China
来源：
RESEARCH ON CHEMICAL INTERMEDIATES | 2012年 / 38卷 / 08期
关键词：
Benzofuran; Carbazole; Methanone; Rap-Stoermer reaction; PEG-400-promoted; Ultrasound-assisted; AGENTS; DERIVATIVES; BENZOFURANS; EFFICIENT; DESIGN;
D O I：
10.1007/s11164-012-0513-1
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A facile synthesis of hitherto unreported benzofuran-2-yl(9-methyl-9H-carbazol-3-yl)methanones (3a-l) is described. The synthesis mainly relies on the ultrasound-assisted Rap-Stoermer reaction of 3-chloroacetyl-9-methyl-9H-carbazole (1) with a variety of salicylaldehydes, as well as 2-hydroxy-1-naphthaldehyde (2) in CH3CN, with the presence of PEG-400 as a catalyst. This procedure offers easy access to benzofuran-2-yl(carbazolyl)methanone derivatives in a short reaction time and the products are achieved in good yields.
引用
收藏
页码：1909 / 1919
页数：11
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