A facile synthesis of novel benzofuran-2-yl(9-methyl-9H-carbazol-3-yl)methanones

被引：4
|
作者：
Zhang, Hong [1 ]
Yan, Yan [1 ]
Li, Yang [1 ]
Gao, Wentao [1 ]
机构：
[1] Bohai Univ, Inst Superfine Chem, Jinzhou 121000, Peoples R China
来源：
RESEARCH ON CHEMICAL INTERMEDIATES | 2012年 / 38卷 / 08期
关键词：
Benzofuran; Carbazole; Methanone; Rap-Stoermer reaction; PEG-400-promoted; Ultrasound-assisted; AGENTS; DERIVATIVES; BENZOFURANS; EFFICIENT; DESIGN;
D O I：
10.1007/s11164-012-0513-1
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A facile synthesis of hitherto unreported benzofuran-2-yl(9-methyl-9H-carbazol-3-yl)methanones (3a-l) is described. The synthesis mainly relies on the ultrasound-assisted Rap-Stoermer reaction of 3-chloroacetyl-9-methyl-9H-carbazole (1) with a variety of salicylaldehydes, as well as 2-hydroxy-1-naphthaldehyde (2) in CH3CN, with the presence of PEG-400 as a catalyst. This procedure offers easy access to benzofuran-2-yl(carbazolyl)methanone derivatives in a short reaction time and the products are achieved in good yields.
引用
收藏
页码：1909 / 1919
页数：11
相关论文
共 50 条
  • [31] Catalytic effect of nano copper ferrite on the synthesis of 6-(anthracen-9-yl)-4-(benzofuran-2-yl)pyrimidin-2-(1H)-one
    Divya, Jaganathan
    Gayathri, Paneerselvam
    Muthuvel, Inbasekaran
    Thirunarayanan, Ganesamoorthy
    OVIDIUS UNIVERSITY ANNALS OF CHEMISTRY, 2023, 34 (02) : 150 - 154
  • [32] 3-[2-(9-Ethyl-9H-carbazol-3-yl)-6-methyl-3-quinolyl]propan-1-ol
    Murugavel, S.
    Ranjith, S.
    SubbiahPandi, A.
    Periyasami, G.
    Raghunathan, R.
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2009, 65 : O139 - U2471
  • [33] Synthesis and Crystal Structure of {4-[2-(9-Hexyl-9H-carbazol-3-yl)vinyl]phenyl} Dimethylamine
    王宏里
    徐文远
    王定理
    张彬
    吴宏
    Chinese Journal of Structural Chemistry, 2007, (06) : 691 - 694
  • [34] Synthesis and Crystal Structure of {4-[2-(9-Hexyl-9H-carbazol-3-yl)vinyl]phenyl} Dimethylamine
    王宏里
    徐文远
    王定理
    张彬
    吴宏
    结构化学, 2007, (06) : 691 - 694
  • [35] Synthesis of 2-(9H-carbazol-1-yl)anilines from 2,3′-biindolyl and ketones
    Noland, Wayland E.
    Brown, Christopher D.
    Zabronsky, Abigail E.
    Tritch, Kenneth J.
    TETRAHEDRON, 2018, 74 (19) : 2391 - 2404
  • [36] 2-(Carbazol-9-yl)acetic acid
    Xie, Min-Hao
    Zou, Pei
    He, Yong-Jun
    Liu, Ya-Ling
    Huang, Biao
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2009, 65 : O2860 - U1820
  • [37] One-pot synthesis of novel 2-(benzofuran-2-yl)-4-phenylquinoline-3-carboxylates
    Gao, Wentao
    Fu, Xinbo
    Zhao, Yanan
    Wang, Dongfang
    JOURNAL OF CHEMICAL RESEARCH, 2017, (01) : 45 - 49
  • [38] Solvent-free microwave assisted synthesis of substituted (E)-phenyl{3-(2-[1-phenyl-3-(thiophen-2-yl)-1H-pyrazol-4-yl]vinyl)benzofuran-2-yl}methanones and their antimicrobial activity
    Ashok, D.
    Ziauddin, M.
    Lakshmi, B. V.
    Sarasija, M.
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2017, 87 (04) : 857 - 862
  • [39] Solvent-free microwave assisted synthesis of substituted (E)-phenyl{3-(2-[1-phenyl-3-(thiophen-2-yl)-1H-pyrazol-4-yl]vinyl)benzofuran-2-yl}methanones and their antimicrobial activity
    D. Ashok
    M. Ziauddin
    B. V. Lakshmi
    M. Sarasija
    Russian Journal of General Chemistry, 2017, 87 : 857 - 862
  • [40] 3,5-bis[(carbazol-9-yl)methyl]-1-methoxybenzene
    Kumar, G. Senthil
    Chinnakali, K.
    Sekar, K.
    Rajakumar, P.
    Fun, Hoong-Kun
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2006, 62 : O3597 - O3599
12345