Electrospinning of bovine serum albumin. Optimization and the use for production of biosensors

被引：87

作者：

Kowalczyk, Tomasz ^{[1
]}

Nowicka, Aleksandra ^{[2
]}

Elbaum, Danek ^{[2
]}

Kowalewski, Tomasz A. ^{[1
]}

机构：

[1] Polish Acad Sci, Inst Fundamental Technol Res, IPPT, PL-00049 Warsaw, Poland

[2] Polish Acad Sci, Inst Phys, IF, PL-02668 Warsaw, Poland

来源：

BIOMACROMOLECULES | 2008年 / 9卷 / 07期

关键词：

D O I：

10.1021/bm800421s

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Electrospinning of the globular protein, bovine serum albumin (BSA), was optimized to obtain proteinous fibers suitable as biosensors. It was shown that the as-spun protein preserves its native form, whereas solubility of the cross-linked in the ambient conditions BSA nanofibers evidently decreases. Insoluble BSA fibers cart be easily modified to be used as two-dimensional biosensors. Here, we show the micro pH sensor obtained from the BSA fiber stained with a fluorescein derivative (FITC).

引用

页码：2087 / 2090

页数：4

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