Structure and Mechanism of the E3 Ligase Rbx1 in Complex with the E2 Enzyme CDC34 Charged with Ubiquitin

被引:0
|
作者
Spratt, Donald E. [1 ]
Mercier, Pascal [1 ]
Pan, Zhen-Qiang [2 ]
Shaw, Gary S. [1 ]
机构
[1] Univ Western Ontario, London, ON, Canada
[2] Mt Sinai Sch Med, New York, NY USA
关键词
D O I
10.1016/j.bpj.2013.11.342
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
引用
收藏
页码:47A / 47A
页数:1
相关论文
共 50 条
  • [31] Phosphorylation of the E3 ubiquitin protein ligase ITCH diminishes binding to its cognate E2 ubiquitin ligase
    Perez, Jessica M.
    Chen, Yinghua
    Xiao, Tsan S.
    Abbott, Derek W.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 293 (03) : 1100 - 1105
  • [32] Arsenite Targets the RING Finger Domain of Rbx1 E3 Ubiquitin Ligase to Inhibit Proteasome-Mediated Degradation of Nrf2
    Jiang, Ji
    Tam, Lok Ming
    Wang, Pengcheng
    Wang, Yinsheng
    CHEMICAL RESEARCH IN TOXICOLOGY, 2018, 31 (05) : 380 - 387
  • [33] E2 Partner Tunes the Ubiquitylation Specificity of Arkadia E3 Ubiquitin Ligase
    Delegkou, Georgia N. N.
    Birkou, Maria
    Fragkaki, Nefeli
    Toro, Tamara
    Marousis, Konstantinos D. D.
    Episkopou, Vasso
    Spyroulias, Georgios A. A.
    CANCERS, 2023, 15 (04)
  • [34] Ubiquitin transfer by a RING E3 ligase occurs from a closed E2~ubiquitin conformation
    Emma Branigan
    J. Carlos Penedo
    Ronald T. Hay
    Nature Communications, 11
  • [35] Ubiquitin transfer by a RING E3 ligase occurs from a closed E2∼ubiquitin conformation
    Branigan, Emma
    Penedo, J. Carlos
    Hay, Ronald T.
    NATURE COMMUNICATIONS, 2020, 11 (01)
  • [36] Spectrin is a chimeric E2/E3 ubiquitin conjugating/ligating enzyme
    Goodman, SR
    FASEB JOURNAL, 2006, 20 (05): : A869 - A869
  • [37] Structure of the DDB1–CRBN E3 ubiquitin ligase in complex with thalidomide
    Eric S. Fischer
    Kerstin Böhm
    John R. Lydeard
    Haidi Yang
    Michael B. Stadler
    Simone Cavadini
    Jane Nagel
    Fabrizio Serluca
    Vincent Acker
    Gondichatnahalli M. Lingaraju
    Ritesh B. Tichkule
    Michael Schebesta
    William C. Forrester
    Markus Schirle
    Ulrich Hassiepen
    Johannes Ottl
    Marc Hild
    Rohan E. J. Beckwith
    J. Wade Harper
    Jeremy L. Jenkins
    Nicolas H. Thomä
    Nature, 2014, 512 : 49 - 53
  • [38] The zinc finger of the CSN-associated deubiquitinating enzyme USP15 is essential to rescue the E3 ligase Rbx1
    Hetfeld, BKJ
    Helfrich, A
    Kapelarl, B
    Scheel, H
    Hofmann, K
    Guterman, A
    Glickman, M
    Schade, R
    Kloetzel, PM
    Dubiel, W
    CURRENT BIOLOGY, 2005, 15 (13) : 1217 - 1221
  • [39] New insights into ubiquitin E3 ligase mechanism
    Berndsen, Christopher E.
    Wolberger, Cynthia
    NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2014, 21 (04) : 301 - 307
  • [40] Mechanism of Activation of the Ubiquitin E3 Ligase, Parkin
    Gehring, Kalle
    Sauve, Veronique
    Sung, George
    Kozlov, Guennadi
    FASEB JOURNAL, 2020, 34