One-pot borylation/amination reactions: Syntheses of arylamine boronate esters from halogenated arenes

被引：42
作者：
Holmes, D [1 ]
Chotana, GA [1 ]
Maleczka, RE [1 ]
Smith, MR [1 ]
机构：
[1] Michigan State Univ, Dept Chem, E Lansing, MI 48824 USA
来源：
ORGANIC LETTERS | 2006年 / 8卷 / 07期
关键词：
D O I：
10.1021/ol060205y
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A one-pot protocol for converting 1,3- and 1,4-substituted aryl halides to arylamine boronate esters is described. This is achieved by sequential Ir-catalyzed aromatic borylation at the least hindered C-H bond of the aryl halide and subsequent Pd-catalyzed CA coupling at the halide position of the crude arylboronic ester.
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收藏
页码：1407 / 1410
页数：4
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