Computer software for performing likelihood tests of pedigree relationship using genetic markers

被引：414

作者：

Goodnight, KF ^{[1
]}

Queller, DC ^{[1
]}

机构：

[1] Rice Univ, Dept Ecol & Evolutionary Biol MS170, Houston, TX 77005 USA

来源：

MOLECULAR ECOLOGY | 1999年 / 8卷 / 07期

关键词：

kinship; likelihood; parentage; pedigree; relatedness; software;

D O I：

10.1046/j.1365-294x.1999.00664.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Molecular techniques are making ever more genetic markers available for use in parentage assignment and measures of relatedness. We present a program, Kinship, designed to use likelihood techniques to test for any non-inbred pedigree relationship between pairs of individuals, using single-locus codominant genetic markers. Kinship calculates the likelihood that each pair of individuals in a data set are related by a given pedigree hypothesis, and likelihood ratios for any pair of hypotheses. The program also uses a simulation routine to attach statistical significance to its results.

引用

页码：1231 / 1234

页数：4

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