Synthesis of 3-[(acetylamino)(aryl)methyl]-4-hydroxycoumarins

被引:13
作者
Anary-Abbasinejad, Mohammad [1 ]
Anaraki-Ardakani, Hossein [1 ]
Saidipoor, Azimeh [1 ]
Shojaee, Mahmood [1 ]
机构
[1] Islamic Azad Univ, Dept Chem, Yazd Branch, Yazd, Iran
关键词
chlorosulfonic acid; 4-hydroxycoumarin; three-component reaction; aryl aldehydes;
D O I
10.3184/030823407X247785
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
One-pot, three-component reaction between aryl aldehydes, 4-hydroxycoumarin, and acetonitrile in the presence of chlorosulfonic acid affords 3-[(acetylamino)(aryl)methyl]-4-hydroxycoumarins in excellent yields.
引用
收藏
页码:535 / 537
页数:3
相关论文
共 16 条
[1]  
Armstrong RW, 1996, CHIMIA, V50, P258
[2]   Montmorillonite K10 clay:: An efficient catalyst for the one-pot stereoselective synthesis of β-acetanxido ketones [J].
Bahulayan, D ;
Das, SK ;
Iqbal, J .
JOURNAL OF ORGANIC CHEMISTRY, 2003, 68 (14) :5735-5738
[3]  
CASIMIR JR, 1995, TETRAHEDRON LETT, V36, P4797
[4]   Multi-component reactions : Emerging chemistry in drug discovery 'From xylocain to crixivan' [J].
Hulme, C ;
Gore, V .
CURRENT MEDICINAL CHEMISTRY, 2003, 10 (01) :51-80
[5]   Applications of N-BOC-diamines for the solution phase synthesis of ketopiperazine libraries utilizing a Ugi/De-BOC/Cyclization (UDC) strategy [J].
Hulme, C ;
Peng, J ;
Louridas, B ;
Menard, P ;
Krolikowski, P ;
Kumar, NV .
TETRAHEDRON LETTERS, 1998, 39 (44) :8047-8050
[6]   The solution phase synthesis of diketopiperazine libraries via the Ugi reaction: Novel application of Armstrong's convertible isonitrile. [J].
Hulme, C ;
Morrissette, MM ;
Volz, FA ;
Burns, CJ .
TETRAHEDRON LETTERS, 1998, 39 (10) :1113-1116
[7]   Remarkable three-step-one-pot solution phase preparation of novel imidazolines utilizing a UDC (Ugi/de-Boc/cyclize) strategy [J].
Hulme, C ;
Ma, L ;
Romano, J ;
Morrissette, M .
TETRAHEDRON LETTERS, 1999, 40 (45) :7925-7928
[8]   Improved procedure for the solution phase preparation of 1,4-benzodiazepine-2,5-dione libraries via Armstrong's convertible isonitrile and the Ugi reaction [J].
Hulme, C ;
Peng, J ;
Tang, SY ;
Burns, CJ ;
Morize, I ;
Labaudiniere, R .
JOURNAL OF ORGANIC CHEMISTRY, 1998, 63 (22) :8021-8023
[9]   Novel safety-catch linker and its application with a Ugi/De-BOC/cyclization (UDC) strategy to access carboxylic acids, 1,4-benzodiazepines, diketopiperazines, ketopiperazines and dihydroquinoxalinones [J].
Hulme, C ;
Peng, J ;
Morton, G ;
Salvino, JM ;
Herpin, T ;
Labaudiniere, R .
TETRAHEDRON LETTERS, 1998, 39 (40) :7227-7230
[10]  
Hulme C, 2003, CURR OPIN DRUG DISC, V6, P921