Coronary Artery Calcification

被引：40

作者：

Osawa, Kazuhiro ^{[1
]}

Nakanishi, Rine ^{[1
]}

Budoff, Matthew ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Los Angeles Biomed Res Inst Harbor, Los Angeles, CA 90095 USA

来源：

GLOBAL HEART | 2016年 / 11卷 / 03期

基金：

美国国家卫生研究院;

关键词：

NONTRADITIONAL RISK MARKERS; AMERICAN-HEART-ASSOCIATION; INTIMA-MEDIA THICKNESS; PANEL III GUIDELINES; C-REACTIVE PROTEIN; CARDIOVASCULAR-DISEASE; CALCIUM SCORE; SUBCLINICAL ATHEROSCLEROSIS; METABOLIC SYNDROME; STATIN THERAPY;

D O I：

10.1016/j.gheart.2016.08.001

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Coronary artery calcification (CAC) is an established marker of subclinical atherosclerosis and an independent predictor of future coronary heart disease in the asymptomatic primary prevention population, particularly in the intermediate risk cohort. CAC also helps in reclassifying those patients and their risk of cardiovascular events into higher or lower risk categories. MESA (Multi-Ethnic Study of Atherosclerosis) is a National Heart, Lung, and Blood Institute-sponsored population-based medical research study involving 6,814 men and women from 6 U.S. communities without a medical history of clinical cardiovascular disease. The evidence from this population cohort revealed that CAC scoring was independently predictive and highly effective at risk stratification of major adverse cardiac events. This review provides available data based on MESA. We focus on the utility of CAC for cardiovascular disease risk stratification of individuals, and we describe its diagnostic value in identifying patients at risk.

引用

页码：287 / 293

页数：7

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