Differentiation induction as a treatment for hematologic malignancies

被引：24
作者：
Miller, WH
Waxman, S
机构：
[1] Mt Sinai Sch Med, Dept Med, New York, NY 10029 USA
[2] McGill Univ, Jewish Gen Hosp, Lady Davis Inst Med Res & SMBD, Montreal, PQ H3T 1E2, Canada
来源：
ONCOGENE | 2002年 / 21卷 / 21期
关键词：
differentiation therapy; acute promyelocytic leukemia; retinoids; arsenic trioxide; transcriptional repression;
D O I：
10.1038/sj/onc/1205328
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：3496 / 3506
页数：11
相关论文
共 120 条
[1]  
AHN MJ, 1995, ONCOGENE, V10, P2307
[2]   Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL [J].
Altucci, L ;
Rossin, A ;
Raffelsberger, W ;
Reitmair, A ;
Chomienne, C ;
Gronemeyer, H .
NATURE MEDICINE, 2001, 7 (06) :680-686
[3]   ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain [J].
Amann, JM ;
Nip, J ;
Strom, DK ;
Lutterbach, B ;
Harada, H ;
Lenny, N ;
Downing, JR ;
Meyers, S ;
Hiebert, SW .
MOLECULAR AND CELLULAR BIOLOGY, 2001, 21 (19) :6470-6483
[4]   Pharmacologic induction of fetal hemoglobin: raising the therapeutic bar in sickle cell disease [J].
Atweh, GF ;
Schechter, AN .
CURRENT OPINION IN HEMATOLOGY, 2001, 8 (02) :123-130
[5]   Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer [J].
Cameron, EE ;
Bachman, KE ;
Myöhänen, S ;
Herman, JG ;
Baylin, SB .
NATURE GENETICS, 1999, 21 (01) :103-107
[6]  
CASTAIGNE S, 1990, BLOOD, V76, P1704
[7]   Retinoic acid and interferon signaling cross talk in normal and RA-resistant APL cells [J].
Chelbi-Alix, MK ;
Pelicano, L .
LEUKEMIA, 1999, 13 (08) :1167-1174
[8]   RETINOIC ACID IS REQUIRED FOR AND POTENTIATES DIFFERENTIATION OF ACUTE PROMYELOCYTIC LEUKEMIA-CELLS BY NONRETINOID AGENTS [J].
CHEN, A ;
LICHT, JD ;
WU, Y ;
HELLINGER, N ;
SCHER, W ;
WAXMAN, S .
BLOOD, 1994, 84 (07) :2122-2129
[9]  
Chen GQ, 1997, BLOOD, V89, P3345
[10]  
Chen GQ, 1996, BLOOD, V88, P1052
12345678910