acyclovir;
drug delivery;
drug formulations;
herpes simplex virus;
microparticles;
microemulsions;
nanoparticles;
vesicles;
D O I:
10.1517/17425240802450340
中图分类号:
R9 [药学];
学科分类号:
1007 ;
摘要:
Herpes viruses (herpes simplex, varicella zoster, cytomegalovirus) are the main cause of a wide variety of human infections. Although the development of successful antiviral agents against infections caused by herpes viruses had been slow until the last decade, the production of delivery systems for acyclovir are a promising alternative. The present review summarizes the principal advances made in developing carriers for the delivery of acyclovir by different routes of administration.