The skin-resident and migratory immune system in steady state and memory: innate lymphocytes, dendritic cells and T cells

被引：253

作者：

Heath, William R. ^{[1
]}

Carbone, Francis R. ^{[1
]}

机构：

[1] Univ Melbourne, Dept Microbiol & Immunol, Parkville, Vic 3052, Australia

来源：

NATURE IMMUNOLOGY | 2013年 / 14卷 / 10期

基金：

英国医学研究理事会; 澳大利亚研究理事会;

关键词：

LYMPHOID STRESS-SURVEILLANCE; LANGERHANS CELLS; ANTIGEN-PRESENTATION; GENITAL HERPES; HAIR FOLLICLE; RETINOIC-ACID; SELF-ANTIGENS; RM CELLS; GAMMA; RECEPTOR;

D O I：

10.1038/ni.2680

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The skin is a highly complex organ interspersed with a variety of smaller organ-like structures and a plethora of cell types that together perform essential functions such as physical sensing, temperature control, barrier maintenance and immunity. In this Review, we outline many of the innate and adaptive immune cell types associated with the skin, focusing on the steady state in mice and men, and include a broad update of dendritic cell function and T cell surveillance.

引用

页码：978 / 985

页数：8

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