Comparative study of the iron cores in human liver ferritin, its pharmaceutical models and ferritin in chicken liver and spleen tissues using Mossbauer spectroscopy with a high velocity resolution

被引：26

作者：

Alenkina, I. V. ^{[1
,2
]}

Oshtrakh, M. I. ^{[1
,2
]}

Klepova, Yu. V. ^{[3
]}

Dubiel, S. M. ^{[4
]}

Sadovnikov, N. V. ^{[3
]}

Semionkin, V. A. ^{[1
,2
]}

机构：

[1] Ural Fed Univ, Inst Phys & Technol, Dept Phys Tech & Devices Qual Control, Ekaterinburg 620002, Russia

[2] Ural Fed Univ, Inst Phys & Technol, Dept Expt Phys, Ekaterinburg 620002, Russia

[3] Ural State Agr Acad, Dept Physiol & Biotechnol, Ekaterinburg 620075, Russia

[4] AGH Univ Sci & Technol, Fac Phys & Appl Comp Sci, PL-30059 Krakow, Poland

来源：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2013年 / 100卷

基金：

俄罗斯基础研究基金会;

关键词：

Mossbauer spectroscopy with a high velocity resolution; Nanosized iron cores; Ferritin; Chicken liver and spleen; Imferon; Maltofer (R); Ferrum Lek;

D O I：

10.1016/j.saa.2012.02.083

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

Application of Mossbauer spectroscopy with a high velocity resolution (4096 channels) for comparative analysis of iron cores in a human liver ferritin and its pharmaceutically important models Imferon, Maltofer (R) and Ferrum Lek as well as in iron storage proteins in chicken liver and spleen tissues allowed to reveal small variations in the Fe-57 hyperfine parameters related to differences in the iron core structure. Moreover, it was shown that the best fit of Mossbauer spectra of these samples required different number of components. The latter may indicate that the real iron core structure is more complex than that following from a simple core-shell model. The effect of different living conditions and age on the iron core in chicken liver was also considered. (C) 2012 Published by Elsevier B.V.

引用

页码：88 / 93

页数：6

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