Regiodivergent Approach to α- and β-(Arylthio)alkenylphosphane Oxides and Sulfides: Aminophosphanes as Synthetic Auxiliaries

被引：6

作者：

Alajarin, Mateo ^{[1
]}

Lopez-Leonardo, Carmen ^{[1
]}

Raja, Rosalia ^{[1
]}

机构：

[1] Univ Murcia, Fac Quim, Dept Quim Organ, E-30100 Murcia, Spain

来源：

SYNLETT | 2008年 / 20期

关键词：

alkynes; aminophosphanes; nucleophilic additions; phosphorus; regioselectivity;

D O I：

10.1055/s-0028-1087416

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

beta-(Arylthio)ethenylphosphane oxides and sulfides are easily prepared by nucleophilic addition of thiophenols to the C C bond of the respective P,P-diphenyl-P-phenylethynyl P(V) derivatives. The regioisomeric alpha-(arylthio) analogues can be also prepared, starting from the same activated alkynes, by sequential nucleophilic addition of aminophosphanes and thiophenols. In these latter cases, aminophosphanes, which are recovered at the end of the processes, act just as synthetic auxiliaries for modulating the regiochemical outcome of the global thiophenol addition.

引用

页码：3172 / 3176

页数：5

共 29 条

[1] Aminophosphanes as iminophosphoranyl synthons:: Efficient P-H addition to activated C=C bonds [J].