A concise enantioselective synthesis of (+)-α-conhydrine

被引：0

作者：

Nagata, K ^{[1
]}

Toriizuka, Y ^{[1
]}

Itoh, T ^{[1
]}

机构：

[1] Showa Univ, Sch Pharmaceut Sci, Shinagawa Ku, Tokyo 1418555, Japan

来源：

HETEROCYCLES | 2005年 / 66卷

关键词：

(+)-alpha-conhydrine; enantioselective synthesis; kinetic resolution; diastereoselective reduction; 2-(1-hydroxypropyl)pyridine;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A short step synthesis of (+)-alpha-conhydrine was achieved employing a kinetic resolution of 2-(1-hydroxypropyl)pyridine with lipase PS and a chelation-controlled diastereoselective reduction of pyridine ring as key reactions.

引用

页码：107 / 109

页数：3

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