Antiviral Triterpenoid Saponins from the Roots of Ilex asprella

被引：39

作者：

Zhou, Min ^{[1
,2
]}

Xu, Min ^{[1
]}

Ma, Xiao-Xia ^{[1
]}

Zheng, Kai ^{[3
]}

Yang, Ke ^{[3
]}

Yang, Chong-Ren ^{[1
]}

Wang, Yi-Fei ^{[3
]}

Zhang, Ying-Jun ^{[1
]}

机构：

[1] Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650201, Heilongtan, Peoples R China

[2] Chinese Acad Sci, Grad Univ, Beijing, Peoples R China

[3] Guangzhou Jinan Biomed Res & Dev Ctr, Guangzhou 510632, Guangdong, Peoples R China

来源：

PLANTA MEDICA | 2012年 / 78卷 / 15期

关键词：

Ilex asprella; Aquifoliaceae; sulfur-containing triterpenoid saponins; asprellanosides A and B; antiviral; IN-VITRO; GLYCOSIDES; LEAVES; PUBESCENS; EMBLICA; CORNUTA;

D O I：

10.1055/s-0032-1315209

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new sulfur-containing triterpenoid saponins, asprellanosides A (1) and B (2), were isolated from the roots of Ilex asprella, together with 10 known compounds (3-12). An in vitro anti-HSV-1 activity test of the isolates (1-4, 6-7, and 9-12) showed that only asprellanoside A (1) and oblonganoside H (6) exhibited anti-HSV-1 activity with TIC values of 0.14 and 0.18 mM, respectively.

引用

页码：1702 / 1705

页数：4

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