Time-Dependent Oxidative Stress Responses of Crucian Carp (Carassius auratus) to Intraperitoneal Injection of Extracted Microcystins

被引：47

作者：

Zhang, X. ^{[2
]}

Xie, P. ^{[1
,2
]}

Li, D. ^{[2
]}

Tang, R. ^{[2
]}

Lei, H. ^{[1
]}

Zhao, Y. ^{[2
]}

机构：

[1] Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol China, Donghu Expt Stn Lake Ecosyst, Wuhan 430072, Peoples R China

[2] Huazhong Agr Univ, Coll Fisheries, Wuhan 430070, Peoples R China

来源：

BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY | 2009年 / 82卷 / 05期

基金：

中国国家自然科学基金;

关键词：

Crucian carp; Extracted microcystins; Oxidative stress; Time-dependent; PLASMA BIOCHEMICAL RESPONSES; RAT-LIVER; EXPOSURE; LR; TISSUES;

D O I：

10.1007/s00128-009-9671-2

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

This study was conducted to investigate time-dependent changes in oxidative enzymes in liver of crucian carp after intraperitoneally injection with extracted microcystins 600 and 150 mu g kg(-1) body weight. The results showed that activities of antioxidant enzymes, including superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase generally exhibited a rapid increase in early phase (1-3 h post injection), but gradually decreased afterwards (12-48 h) compared with the control, with an evident time-dependent effect. These zigzag changes over time contributed a better understanding on oxidative stress caused by microcystins in fish.

引用

页码：574 / 578

页数：5

共 17 条

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[3]

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