Protein folding in a force clamp

被引：11

作者：

Cieplak, Marek

Szymczak, P.

机构：

[1] Polish Acad Sci, Inst Phys, PL-02668 Warsaw, Poland

[2] Univ Warsaw, Inst Theoret Phys, PL-00681 Warsaw, Poland

来源：

JOURNAL OF CHEMICAL PHYSICS | 2006年 / 124卷 / 19期

关键词：

D O I：

10.1063/1.2192768

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Kinetics of folding of a protein held in a force clamp are compared to an unconstrained folding. The comparison is made within a simple topology-based dynamical model of ubiquitin. We demonstrate that the experimentally observed variations in the end-to-end distance reflect microscopic events during folding. However, the folding scenarios in and out of the force clamp are distinct. (c) 2006 American Institute of Physics.

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页数：4

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