Cardiac and renal structure and function and quality of life in patients with chronic heart failure and chronic obstructive pulmonary disease

The study included 80 patients with chronic heart failure (CHF) and chronic obstructive pulmonary disease (COPD) at Day 25-30 after myocardial infarction. All patients underwent clinical examination with CHF junctional class identification, echocardiography, 24-hour electrocardiography monitoring, pulmonary and renal function evaluation, and quality of life assessment. Among patients with CHF and COPD, comparing to patients with intact pulmonary function, angina attacks, cardiac arrhythmias and tachycardia were more prevalent, as well as reduced left ventricular systolic and diastolic function and disadaptive myocardial remodelling. In CHF patients, pulmonary dysfunction affected nitrogen-excretory and filtration renal function and aggravated intra-glomerular hypertension.