Fat necrosis may mimic local recurrence of breast cancer in FDG PET/CT

Fat necrosis of the breast is a benign condition that most commonly occurs as the result of trauma. The radiographic and clinical significance of fat necrosis of the breast is that it may mimic malignancy. We present a case of false positive FDG PET/CT scan caused by fat necrosis and mimics local recurrence of breast carcinoma 3 years after radical mastectomy. Physicians must be aware of fat necrosis as a potential pitfall for PET/CT. Fat necrosis must be considered in the differential diagnosis of hypermetabolic breast masses in patients who previously had mastectomy or mammoplasty. (c) 2012 Elsevier Espana, S.L. and SEMNIM. All rights reserved.