Cleavage of the THP protecting group under Pd/C-catalyzed hydrogenation conditions

被引：16

作者：

Kaisalo, LH ^{[1
]}

Hase, TA ^{[1
]}

机构：

[1] Univ Helsinki, Dept Chem, Organ Chem Lab, FIN-00014 Helsinki, Finland

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 43期

关键词：

D O I：

10.1016/S0040-4039(01)01630-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Alcohol and phenol THP or ethoxyethyl ether protecting groups may be cleaved in high yield under Pd/C-catalyzed hydrogenation conditions in EtOH, owing to the inadvertent presence of small quantities of HCl in the reaction mixture. MOM ethers are not cleaved under these conditions. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：7699 / 7701

页数：3

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