May sediment contamination be xenoestrogenic to benthic fish? A case study with Solea senegalensis

被引：17

作者：

Goncalves, Catia ^{[1
]}

Martins, Marta ^{[1
,2
]}

Diniz, Mario S. ^{[3
]}

Costa, Maria H. ^{[1
]}

Caeiro, Sandra ^{[1
,4
,5
]}

Costa, Pedro M. ^{[1
]}

机构：

[1] Univ Nova Lisboa, Fac Ciencias & Tecnol, IMAR, Dept Ciencias Engerzharia Ambiente, P-2829516 Caparica, Portugal

[2] IPMA, P-1449006 Lisbon, Portugal

[3] Univ Nova Lisboa, REQUIMTE, Fac Ciencias & Tecnol, Dept Quim, P-2829516 Caparica, Portugal

[4] Univ Aberta, Rua Escola Politecn, Dept Ciencias Tecnol, P-1269001 Lisbon, Portugal

[5] Univ Nova Lisboa, Fac Ciencias & Tecnol, Ctr Environm & Sustainabil Res, CENSE, P-2829516 Caparica, Portugal

来源：

MARINE ENVIRONMENTAL RESEARCH | 2014年 / 99卷

关键词：

Flatfish; EDCs; Pollution monitoring; Mixtures; Vitellogenin; CYP1A; EROD; FLOUNDER PLATICHTHYS-FLESUS; BIOCHEMICAL END-POINTS; SEX STEROID-LEVELS; ESTROGENIC CONTAMINATION; RISK-ASSESSMENT; ENDOCRINE DISRUPTION; VITELLOGENIN LEVELS; CYTOCHROME-P450; 1A; UNITED-KINGDOM; TAGUS ESTUARY;

D O I：

10.1016/j.marenvres.2014.04.012

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Within an environmental risk assessment framework of a moderately contaminated estuary (the Sado, SW Portugal), the present work intended to detect endocrine disruption in a flatfish, Solea senegalensis Kaup, 1858, and its potential relationship to organic toxicants. Animals were collected from two distinct areas in the estuary (industrial and rural) and from an external reference area. Hepatic vitellogenin (VTG) levels, cytochrome P450 (CYP1A) induction, ethoxyresorufin-O-deethylase (EROD) activity plus gonad histology were analysed. Males and females were sexually immature and showed no significant evidence of degenerative pathologies. However, hepatic VTG concentrations in males from the industrial area were higher than Reference, even reaching levels comparable to females, indicating low but measurable oestrogenic effects caused by the complex contaminant mixture in estuarine sediments. These individuals also presented elevated CYP1A induction and EROD activity, which is consistent with contamination by organic toxicants such as PAHs and other aryl hydrocarbon receptor (Ahr) -mediated toxicants. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：170 / 178

页数：9

共 63 条

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