Microfluidics applied to Love-wave devices to detect biological warfare agents in dynamic mode

被引：0

作者：

Matatagui, D. ^{[1
]}

Fontecha, J. ^{[1
]}

Fernandez, M. J. ^{[1
]}

Santos, J. P. ^{[1
]}

Horrillo, M. C. ^{[1
]}

Gracia, I. ^{[2
]}

Cane, C. ^{[2
]}

机构：

[1] CSIC, Inst Seguridad Informac, GRIDSEN, Madrid, Spain

[2] CSIC, Inst Microelectron Barcelona, Barcelona, Spain

来源：

PROCEEDINGS OF THE 2013 SPANISH CONFERENCE ON ELECTRON DEVICES (CDE 2013) | 2013年

关键词：

Acoustic wave sensor; Love wave; microfluidics; immunodetection; biosensor; BIOSENSOR;

D O I：

暂无

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

A Love-wave device combined with a microfluidic chip of PDMS has been developed to detect biological warfare agents (BWA) in liquid media. It has been tested with the realization of two immunoassays: in the first one the bacteriophage M13 has been detected through the mouse monoclonal antibody, anti-M13 (AM13), and in the second one the detection has been carried out by means of the immunoreaction of the rabbit immunoglobulin (Rabbit IgG) with the goat anti-rabbit polyclonal antibody (GAR). The detections have been performed in a dynamic mode (continuous flow-through) in order to obtain a short response time. Different concentrations have been detected with a fast response and a good discrimination among them.

引用

页码：115 / 118

页数：4

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