Microfluidics applied to Love-wave devices to detect biological warfare agents in dynamic mode

被引：0
|
作者：
Matatagui, D. [1 ]
Fontecha, J. [1 ]
Fernandez, M. J. [1 ]
Santos, J. P. [1 ]
Horrillo, M. C. [1 ]
Gracia, I. [2 ]
Cane, C. [2 ]
机构：
[1] CSIC, Inst Seguridad Informac, GRIDSEN, Madrid, Spain
[2] CSIC, Inst Microelectron Barcelona, Barcelona, Spain
来源：
PROCEEDINGS OF THE 2013 SPANISH CONFERENCE ON ELECTRON DEVICES (CDE 2013) | 2013年
关键词：
Acoustic wave sensor; Love wave; microfluidics; immunodetection; biosensor; BIOSENSOR;
D O I：
暂无
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
A Love-wave device combined with a microfluidic chip of PDMS has been developed to detect biological warfare agents (BWA) in liquid media. It has been tested with the realization of two immunoassays: in the first one the bacteriophage M13 has been detected through the mouse monoclonal antibody, anti-M13 (AM13), and in the second one the detection has been carried out by means of the immunoreaction of the rabbit immunoglobulin (Rabbit IgG) with the goat anti-rabbit polyclonal antibody (GAR). The detections have been performed in a dynamic mode (continuous flow-through) in order to obtain a short response time. Different concentrations have been detected with a fast response and a good discrimination among them.
引用
收藏
页码：115 / 118
页数：4
相关论文
共 10 条
  • [1] Love-Wave Sensors Combined with Microfluidics for Fast Detection of Biological Warfare Agents
    Matatagui, Daniel
    Luis Fontecha, Jose
    Jesus Fernandez, Maria
    Gracia, Isabel
    Cane, Carles
    Pedro Santos, Jose
    Carmen Horrillo, Maria
    SENSORS, 2014, 14 (07): : 12658 - 12669
  • [2] Detection of bacteriophages in dynamic mode using a Love-wave immunosensor with microfluidics technology
    Matatagui, D.
    Moynet, D.
    Fernandez, M. J.
    Fontecha, J.
    Esquivel, J. P.
    Gracia, I.
    Cane, C.
    Dejous, C.
    Rebiere, D.
    Santos, J. P.
    Horrillo, M. C.
    SENSORS AND ACTUATORS B-CHEMICAL, 2013, 185 : 218 - 224
  • [3] Comparison of two types of acoustic biosensors to detect immunoreactions: Love-wave sensor working in dynamic mode and QCM working in static mode
    Matatagui, D.
    Fontecha, J.
    Fernandez, M. J.
    Oliver, M. J.
    Hernando-Garcia, J.
    Sanchez-Rojas, J. L.
    Gracia, I.
    Cane, C.
    Santos, J. P.
    Horrillo, M. C.
    SENSORS AND ACTUATORS B-CHEMICAL, 2013, 189 : 123 - 129
  • [4] Love-wave sensor array to detect, discriminate and classify chemical warfare agent simulants
    Matatagui, D.
    Fernandeza, M. J.
    Fontecha, J.
    Santos, J. P.
    Gracia, I.
    Cane, C.
    Horrillo, M. C.
    SENSORS AND ACTUATORS B-CHEMICAL, 2012, 175 : 173 - 178
  • [5] Array of Love-wave sensors based on quartz/Novolac to detect CWA simulants
    Matatagui, D.
    Fontecha, J.
    Fernandez, M. J.
    Aleixandre, M.
    Gracia, I.
    Cane, C.
    Horrillo, M. C.
    TALANTA, 2011, 85 (03) : 1442 - 1447
  • [6] The BARC biosensor applied to the detection of biological warfare agents
    Edelstein, RL
    Tamanaha, CR
    Sheehan, PE
    Miller, MM
    Baselt, DR
    Whitman, LJ
    Colton, RJ
    BIOSENSORS & BIOELECTRONICS, 2000, 14 (10-11) : 805 - 813
  • [7] Discrimination and classification of chemical warfare agent simulants using a Love-wave sensor array
    Matatagui, D.
    Fernandez, M. J.
    Fontecha, J.
    Santos, J. P.
    Gracia, I.
    Cane, C.
    Horrillo, M. C.
    EUROSENSORS XXV, 2011, 25
  • [8] Multi-Mode Love-Wave SAW Magnetic-Field Sensors
    Schmalz, Julius
    Kittmann, Anne
    Durdaut, Phillip
    Spetzler, Benjamin
    Faupel, Franz
    Hoeft, Michael
    Quandt, Eckhard
    Gerken, Martina
    SENSORS, 2020, 20 (12) : 1 - 17
  • [9] Comparative evaluation between two acoustic immunosensors: Love-wave and QCM, and systems of measurement: dynamic and static
    Matatagui, D.
    Fontecha, J.
    Fernandez, M. J.
    Oliver, M. J.
    Hernando-Garcia, J.
    Sanchez-Rojas, J. L.
    Gracia, I.
    Cane, C.
    Santos, J. P.
    Horrillo, M. C.
    26TH EUROPEAN CONFERENCE ON SOLID-STATE TRANSDUCERS, EUROSENSOR 2012, 2012, 47 : 174 - 177
  • [10] Love-mode surface acoustic wave devices based on multilayers of TeO2/ZnO(11(2)over-bar0)/Si(100) with high sensitivity and temperature stability
    Luo, Jing-Ting
    Quan, Ao-Jie
    Liang, Guang-Xing
    Zheng, Zhuang-Hao
    Ramadan, Sami
    Fu, Chen
    Li, Hong-Lang
    Fu, Yong-Qing
    ULTRASONICS, 2017, 75 : 63 - 70
1