The Clinical Utility of Tumor Markers

Tumor markers provide a minimally invasive cost-effective source of data valuable for monitoring disease course determining prognosis, and aiding in treatment planning. A understanding of the individual test characteristics and limitations, however, is important for optimal use and accurate interpretation of results. A variety of types of markers are available in the routine clinical laboratory including enzymes, oncofetal antigens oncogene products, monoclonal antibody-defined epitopes, and hormones. The clinical applications and limitations of some that are currently in widespread use will be discussed.