Association Between Postexercise Hypotension and Long-term Training-Induced Blood Pressure Reduction: A Pilot Study

Objective: The interindividual variability in the efficacy of regular endurance exercise to lower blood pressure is high. Therefore, to optimize training prescriptions, predictors would be desirable. The main hypothesis of the present study was an association between postexercise hypotension after an exhaustive exercise test and chronic blood pressure reductions in response to an endurance training program. Design: Uncontrolled prospective training study. Setting: University department. Participants: Healthy untrained subjects were recruited by flyers. Inclusion criteria were age 30 to 60 years, body mass index 25 to 35 kg/m(2), untrained status (<1 hour/week regular activity; (V) over dotO(2max) < 45 mL.min(-1).kg(-1)), blood pressure 150/95 mm Hg, nonsmoker; 14 subjects were included, 12 could be analyzed. Intervention: Walking/running 4 times per week at 60% heart rate reserve for 4 weeks. Main Outcome Measures: Difference in blood pressure from the initial resting value to 1 and 24 hours after the initial test (acute) and the resting value before the final test (chronic), respectively. Results: Initial resting systolic blood pressure was 134 +/- 18 mm Hg. Values were significantly reduced at all time points thereafter (1 hour: 125 +/- 13 mm Hg; 24 hours: 128 +/- 12 mm Hg; final: 125 +/- 18 mm Hg). Acute and chronic changes correlated significantly (1 hour: P = 0.003; r = 0.77; 24 hours: P = 0.017; r = 0.67). Results for diastolic blood pressure were comparable yet less pronounced. Conclusions: The magnitude of postexercise hypotension is a promising candidate for the prediction of individual blood pressure-related training efficacy. Easily determined, it might be used to improve training prescriptions. However, further studies are needed to assess predictive accuracy.