Chemical composition and biological potential of Thymus Willdenowii Boiss. & Reut. essential oil

被引：9

作者：

Zeghib, Assia ^{[1
]}

Calliste, Claude-Alain ^{[2
]}

Simon, Alain ^{[3
]}

Charfeddine, Rim ^{[4
]}

Aouni, Mahjoub ^{[4
]}

Duroux, Jean-Luc ^{[2
]}

Kabouche, Ahmed ^{[1
]}

Kabouche, Zahia ^{[1
]}

机构：

[1] Univ Freres Mentouri Constantine 1, LOST, Dept Chim, Constantine 25000, Algeria

[2] Univ Limoges, Inst GEIST, Lab Biophys, Fac Pharm,EA LCSN 1069, Limoges, France

[3] Univ Limoges, Inst GEIST, Lab Chim Phys & Minerale, Fac Pharm,EA LCSN 1069, Limoges, France

[4] Univ Monastir, Fac Pharm, Lab Malad Transmissibles & Subst Biologiquement A, Monastir, Tunisia

来源：

NATURAL PRODUCT RESEARCH | 2021年 / 35卷 / 05期

关键词：

Thymus willdenowii Boiss & Reut; essential oil; cytotoxicity; antibacterial; antiproliferative; antioxidant; antiviral; ANTIOXIDANT;

D O I：

10.1080/14786419.2019.1602830

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The fresh aerial parts of Thymus willdenowii Boiss. & Reut. (syn. Thymus hirtus Willd.) were hydrodistilled in a Clevenger type apparatus and analyzed by GC and GC-MS. 44 Components were identified representing 97.3%, with 1,8-cineole (34.62%), camphor (18.55%), alpha-pinene (9.46%) and camphene (5.38%) as the main components. T. willdenowii essential oil was not cytotoxic (CC50 = 97.65 mu g/mL) towards Vero non-tumoural cells, exhibiting good antibacterial and antiproliferative (30.8 +/- 3.1% inhibition) potentials against four tested pathogenic bacteria and Human colorectal cell line HT-29, respectively. The essential oil did not show a DPPH radical scavenging activity, by Electron Spin Resonance spectroscopy (ESR), and it lacks antiviral effect towards coxsackievirus B3. [GRAPHICS] .

引用

页码：845 / 848

页数：4

共 14 条

[1]

Belmalha S., 2015, GLOB J PURE APPL CHE, V3, P43

[2]

Ben Bnina E, 2009, J ESSENT OIL RES, V21, P567

[3] COMPOSITION AND ANTIOXIDANT ACTIVITY OF THE ESSENTIAL OIL OF Thymus dreatensis FROM ALGERIA [J].

Ferhat, M. ;

Ghorab, H. ;

Laggoune, S. ;

Ghannadi, A. ;

Sajjadi, S. E. ;

Touzani, R. ;

Kabouche, A. ;

Kabouche, Z. .

CHEMISTRY OF NATURAL COMPOUNDS, 2014, 50 (04) :747-749

[4]

Ghannadi A, 2004, Z NATURFORSCH C, V59, P187

[5] Ethnopharmacology of Lippia alba [J].

Hennebelle, Thierry ;

Sahpaz, Sevser ;

Joseph, Henry ;

Bailleul, Francois .

JOURNAL OF ETHNOPHARMACOLOGY, 2008, 116 (02) :211-222

[6] Analysis of the essential oil of Thymus numidicus (Poiret) from Algeria [J].

Kabouche, A ;

Kabouche, Z ;

Bruneau, C .

FLAVOUR AND FRAGRANCE JOURNAL, 2005, 20 (02) :235-236

[7]

Kabouche A, 2009, NAT PROD COMMUN, V4, P1251

[8]

Kabouche Z., 2005, International Journal of Aromatherapy, V15, P129, DOI 10.1016/j.ijat.2005.03.006

[9]

Ouknin M, 2018, NAT PROD RES

[10]

Quezel P., 1963, Nouvelle flore de l'Algerie et des regions desertoriques meridionales, Tome, V2

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