A Ratiometric Fluorescent Probe for Biological Signaling Molecule H2S: Fast Response and High Selectivity

被引：150

作者：

Liu, Jing ^{[1
]}

Sun, Yuan-Qiang ^{[1
]}

Zhang, Jingyu ^{[1
]}

Yang, Ting ^{[2
]}

Cao, Jianbin ^{[3
]}

Zhang, Lishen ^{[1
]}

Guo, Wei ^{[1
]}

机构：

[1] Shanxi Univ, Sch Chem & Chem Engn, Taiyuan 030006, Peoples R China

[2] Shanxi Univ, Inst Biotechnol, Taiyuan 030006, Peoples R China

[3] Shanxi Univ, Res Inst Appl Chem, Taiyuan 030006, Peoples R China

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2013年 / 19卷 / 15期

关键词：

addition reaction; biosensors; fluorescence spectroscopy; fluorescent probes; hydrogen sulfide; ENDOGENOUS HYDROGEN-SULFIDE; RAPID DETECTION; 3RD GAS; CYSTEINE; SENSOR; BLOOD; CELLS; IONS;

D O I：

10.1002/chem.201300455

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Selective and fast: A flavylium derivative-based ratiometric fluorescent probe (1) for H2S is reported. The reaction mechanism (see scheme) is based on the nucleophilic addition of H2S towards the electrically positive benzopyrylium moiety of 1, which can efficiently differentiate H 2S from other competitive species. The probe exhibits a fast response toward H2S, within 10 s, which is superior to most of the reported H2S probes. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：4717 / 4722

页数：6

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