Enantioselective Synthesis of Optically Active 3,3-Diarylpropanoates by Conjugate Hydrosilylation with Chiral Rh-bis(oxazolinyl)phenyl Catalysts

被引：25

作者：

Itoh, Kengou ^{[1
]}

Tsuruta, Ayae ^{[1
]}

Ito, Jun-ichi ^{[1
]}

Yamamoto, Yoshihiko ^{[1
]}

Nishiyama, Hisao ^{[1
]}

机构：

[1] Nagoya Univ, Dept Appl Chem, Grad Sch Engn, Chikusa Ku, Nagoya, Aichi 4648603, Japan

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2012年 / 77卷 / 23期

基金：

日本学术振兴会;

关键词：

ALPHA; BETA-UNSATURATED CARBONYL-COMPOUNDS; ASYMMETRIC HYDROGENATION; ARYLBORONIC ACIDS; REDUCTION; ESTERS; SUBSTITUENTS; NITROALKENES; COMPLEXES; SULFONES; RECEPTOR;

D O I：

10.1021/jo302357b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Conjugate hydrosilylation of 3,3-diarylacrylate derivatives catalyzed by chiral rhodium-bis(oxazolinyl)phenyl complexes (1 mol %) at 60 degrees C for 2 h was investigated to prepare optically active 3,3-diarylpropanoate derivatives in high yields up to 99% yield and high enantioselectivities up to 99%.

引用

页码：10914 / 10919

页数：6

共 3 条

[1] Enantioselective Synthesis of Optically Active Bis(β-hydroxy) Sulfones through Asymmetric Hydrogenation of Corresponding Ketones Catalyzed by a Chiral Cationic Ruthenium Diamine Catalyst
Huang, Xiaofei
Zhao, Min
Li, Naikai
Li, Haiyan
Li, Jie
Wang, Xingwang
CHINESE JOURNAL OF CHEMISTRY, 2014, 32 (08) : 803 - 813
[2] Synthesis of optically active 3,3′-disubstituted biphenyl derivatives using palladium-catalyzed amination and their evaluation as enantioselective fluorescent detectors for amino alcohols and metal cations
Shaferov, A. V.
Malysheva, A. S.
Averin, A. D.
Grigorova, O. K.
Buryak, A. K.
Beletskaya, I. P.
RUSSIAN CHEMICAL BULLETIN, 2020, 69 (07) : 1366 - 1377
[3] Synthesis of Optically Active Spiro Compounds with a 3,3′-(4H,4′H)-Spirobi(2H-naphtho[1,2-b]pyran) Skeleton and Their Applications as Chiral Dopants for Nematic Liquid Crystals
Tojo, Kenta
Arisawa, Tatsuya
Aoki, Yoshio
Terunuma, Daiyo
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 2009, 82 (04) : 519 - 527

← 1 →