Nitration of tert-butyloxycarbonylated aniline and 1,3,5-triaminobenzene by acetyl nitrate

被引：5

作者：

Davis, Matthew C. ^{[1
]}

Groshens, Thomas J. ^{[1
]}

机构：

[1] USN, Chem & Mat Div, Air Warfare Ctr, China Lake, CA 93555 USA

来源：

TETRAHEDRON LETTERS | 2012年 / 53卷 / 32期

关键词：

Aromatic nitration; Acetyl nitrate; Aniline; Boc-protection; REGIOSELECTIVE NITRATION; AROMATIC-SUBSTITUTION; ACID; REARRANGEMENT; ACETANILIDES; PRECURSOR; MECHANISM; GLUTAMATE;

D O I：

10.1016/j.tetlet.2012.05.139

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Acetyl nitrate was found to be an effective reagent for aromatic mono- and dinitration of Boc-protected aminobenzenes. The method was used in a new synthesis of 1,35-triamino-2,4-dinitrobenzene in two steps with 63% yield. Published by Elsevier Ltd.

引用

页码：4154 / 4155

页数：2

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