Formation of giant unilamellar vesicles from spin-coated lipid films by localized IR heating

被引:21
作者
Billerit, Celine [1 ]
Jeffries, Gavin D. M. [1 ]
Orwar, Owe [1 ]
Jesorka, Aldo [1 ]
机构
[1] Chalmers Univ Technol, Dept Chem & Biol Engn, SE-41296 Gothenburg, Sweden
基金
欧洲研究理事会;
关键词
LIPOSOMES; ELECTROFORMATION; FUSION; STATE;
D O I
10.1039/c2sm26394g
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
We report a novel method for the generation of GUVs (generate unilamellar vesicles) from spin-coated lipid films by means of localized heating. This technique enables GUV formation from both charged and neutral lipid species, as well as from a complex lipid mixture, in various ionic strength conditions. Encapsulation was possible during and after GUV formation.
引用
收藏
页码:10823 / 10826
页数:4
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