Performance of the over-the-scope clip system in the endoscopic closure of iatrogenic gastrointestinal perforations and post-surgical leaks and fistulas

被引:14
作者
Iabichino, Giuseppe [1 ]
Eusebi, Leonardo H. [2 ]
Palamara, Maria A. [1 ]
Arena, Monica [1 ]
Pellicano, Rinaldo [3 ]
Consolo, Pierluigi [4 ]
Fagoonee, Sharmila [5 ]
Amato, Loretta [1 ]
Opocher, Enrico [6 ]
Barabino, Matteo [6 ]
Luigiano, Carmelo [1 ]
机构
[1] San Paolo Hosp, Unit Digest Endoscopy, Via A Di Rudini 8, I-20142 Milan, Italy
[2] Univ Bologna, Dept Surg & Med Sci, Bologna, Italy
[3] Molinette Mauriziano Hosp, Dept Gastrohepatol, Turin, Italy
[4] Univ Messina, Hosp G Martino, Dept Med & Pharmacol, Messina, Italy
[5] Univ Turin, CNR, Ctr Mol Biotechnol, Inst Biostruct & Bioimages, Turin, Italy
[6] Univ Milan, San Paolo Hosp, Dept Surg, Unit Hepatobilyopancreat & Digest Surg, Milan, Italy
关键词
Iatrogenic disease; Endoscopy; gastrointestinal; Fistula; 1ST CLINICAL-EXPERIENCES; LOW ANTERIOR RESECTION; CASE SERIES; ANASTOMOTIC LEAK; OTSC SYSTEM; COLONOSCOPIC PERFORATIONS; GASTROCUTANEOUS FISTULA; MULTICENTER EXPERIENCE; SINGLE-INSTITUTION; TRACT PERFORATIONS;
D O I
10.23736/S1121-421X.17.02439-4
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The increased invasiveness of endoscopic procedures and complex surgical interventions has resulted in an increased number of gastrointestinal iatrogenic defects, such as perforations, leak and fistulas. The conventional treatment for these gastrointestinal defects is surgery, with considerable risks especially in emergency situations and in patients with comorbidities. The Ovesco over-the-scope clip (OTSC) system (Ovesco Endoscopy AG, Tubingen, Germany) and more recently, the Padlock Clip (TM) (Aponos Medical, Kingston, NH, USA) have shown promising results in the treatment of gastrointestinal defects. Several case reports and case series have demonstrated the efficacy of the OTSC system for the closure of full-thickness defects. Clinical success is best achieved in patients undergoing closure of a perforation or a leak. Closure of fistulas remains a clinical challenge since fibrosis or necrotic and inflamed tissue surrounding lesions may cause clip failure. Over-the-scope clips are a less invasive endoscopic option for managing patients with gastrointestinal defects before a more invasive surgical approach is attempted. Moreover, a failed attempt of OTSC deployment does not preclude subsequent surgical treatment.
引用
收藏
页码:75 / 83
页数:9
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