Contribution of RIPK1 kinase activity to cell death induced by anti-cancer agents using 7-CI-O-Nec-1, a potent and highly selective RIPK1 kinase inhibitor

被引：0
|
作者：
Alavi, Alireza
Benetatos, Christopher
Yuan, Junying
Degterev, Alexei
Franklin, Jessica
Condon, Stephen
McKinlay, Mark
Chunduru, Srinivas
机构：
[1] TetraLog Pharmaceut Corp, Malvern, PA USA
[2] Harvard Univ, Sch Med, Boston, MA USA
[3] Tufts Univ, Sch Med, Boston, MA 02111 USA
来源：
CANCER RESEARCH | 2009年 / 69卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
2036
引用
收藏
页数：1
相关论文
共 35 条
  • [31] Small-Molecule Parkinson's Disease Kinase Inhibitor LRRK2-in-1 Demonstrates Potent Anti-Cancer Activity Through Inhibition of DCLK1
    Weygant, Nathaniel
    Qu, Dongfeng
    Berry, William L.
    May, Randal
    Chandrakesan, Parthasarathy
    Owen, Daniel
    Ali, Naushad
    Janknecht, Ralf
    Sureban, Sripathi M.
    Houchen, Courtney W.
    GASTROENTEROLOGY, 2014, 146 (05) : S694 - S694
  • [32] Identification of 5-(2,3-Dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Derivatives as a New Class of Receptor-Interacting Protein Kinase 1 (RIPK1) Inhibitors, Which Showed Potent Activity in a Tumor Metastasis Model
    Li, Yueshan
    Xiong, Yu
    Zhang, Guo
    Zhang, Liting
    Yang, Wei
    Yang, Jiao
    Huang, Luyi
    Qiao, Zeen
    Miao, Zhuang
    Lin, Guifeng
    Sun, Qiu
    Niu, Ting
    Chen, Lijuan
    Niu, Dawen
    Li, Linli
    Yang, Shengyong
    JOURNAL OF MEDICINAL CHEMISTRY, 2018, 61 (24) : 11398 - 11414
  • [33] Identification of 5-(2,3-Dihydro-1H-indo1-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Derivatives as a New Class of Receptor-Interacting Protein Kinase 1 (RIPK1) Inhibitors, Which Showed Potent Activity in a Tumor Metastasis Model (vol 61, pg 11398, 2018)
    Li, Yueshan
    Xiong, Yu
    Zhang, Guo
    Zhang, Liting
    Yang, Wei
    Yang, Jiao
    Huang, Luyi
    Qiao, Zeen
    Miao, Zhuang
    Lin, Guifeng
    Sun, Qiu
    Niu, Ting
    Chen, Lijuan
    Niu, Dawen
    Li, Linli
    Yang, Shengyong
    JOURNAL OF MEDICINAL CHEMISTRY, 2019, 62 (06) : 3169 - 3169
  • [34] Nutritional and chemopreventive anti-cancer agents up-regulate expression of p27Kip1, a cyclin-dependent kinase inhibitor, in mouse JB6 epidermal and human MCF7, MDA-MB-321 and AU565 breast cancer cells
    Eto, Isao
    CANCER CELL INTERNATIONAL, 2006, 6 (1)
  • [35] "Nutritional and chemopreventive anti-cancer agents up-regulate expression of p27Kip1, a cyclin-dependent kinase inhibitor, in mouse JB6 epidermal and human MCF7, MDA-MB-321 and AU565 breast cancer cells"
    Isao Eto
    Cancer Cell International, 6
1234