Contribution of RIPK1 kinase activity to cell death induced by anti-cancer agents using 7-CI-O-Nec-1, a potent and highly selective RIPK1 kinase inhibitor

被引：0
|
作者：
Alavi, Alireza
Benetatos, Christopher
Yuan, Junying
Degterev, Alexei
Franklin, Jessica
Condon, Stephen
McKinlay, Mark
Chunduru, Srinivas
机构：
[1] TetraLog Pharmaceut Corp, Malvern, PA USA
[2] Harvard Univ, Sch Med, Boston, MA USA
[3] Tufts Univ, Sch Med, Boston, MA 02111 USA
来源：
CANCER RESEARCH | 2009年 / 69卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
2036
引用
收藏
页数：1
相关论文
共 35 条
  • [21] K63-linked ubiquitination regulates RIPK1 kinase activity to prevent cell death during embryogenesis and inflammation
    Tang, Yong
    Tu, Hailin
    Zhang, Jie
    Zhao, Xueqiang
    Wang, Yini
    Qin, Jun
    Lin, Xin
    NATURE COMMUNICATIONS, 2019, 10 (1)
  • [22] K63-linked ubiquitination regulates RIPK1 kinase activity to prevent cell death during embryogenesis and inflammation
    Yong Tang
    Hailin Tu
    Jie Zhang
    Xueqiang Zhao
    Yini Wang
    Jun Qin
    Xin Lin
    Nature Communications, 10
  • [23] Discovery of a cross-species potent and selective inhibitor of receptor-interacting protein kinase 1 (RIPK1) providing protection in a Nemo deletion model of IBD
    Patel, Snahel
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 256
  • [24] Caspase-8, receptor-interacting protein kinase 1 (RIPK1), and RIPK3 regulate retinoic acid-induced cell differentiation and necroptosis
    Someda, Masataka
    Kuroki, Shunsuke
    Miyachi, Hitoshi
    Tachibana, Makoto
    Yonehara, Shin
    CELL DEATH AND DIFFERENTIATION, 2020, 27 (05): : 1539 - 1553
  • [25] Caspase-8, receptor-interacting protein kinase 1 (RIPK1), and RIPK3 regulate retinoic acid-induced cell differentiation and necroptosis
    Masataka Someda
    Shunsuke Kuroki
    Hitoshi Miyachi
    Makoto Tachibana
    Shin Yonehara
    Cell Death & Differentiation, 2020, 27 : 1539 - 1553
  • [26] Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) inhibitors Necrostatin-1 (Nec-1) and 7-Cl-O-Nec-1 (Nec-1s) are potent inhibitors of NAD(P)H: Quinone oxidoreductase 1 (NQO1)
    Yu, Jie
    Zhong, Bingling
    Zhao, Lin
    Hou, Ying
    Wang, Xianzhe
    Chen, Xiuping
    FREE RADICAL BIOLOGY AND MEDICINE, 2021, 173 : 64 - 69
  • [27] The cell death-associated protein kinase, RIPK1, is phosphorylated in cardiomyocytes in response to pro-inflammatory cytokines or oxidative stress
    Rostron, K. A.
    Leonard, S. J.
    Fuller, S. J.
    Sugden, P. H.
    Clerk, A.
    EUROPEAN JOURNAL OF HEART FAILURE, 2017, 19 : 514 - 514
  • [28] Differential involvement of TAK1, RIPK1 and NF-κB signaling in Smac mimetic-induced cell death in breast cancer cells
    Schmidt, Nadine
    Kowald, Lisa
    van Wijk, Sjoerd J. L.
    Fulda, Simone
    BIOLOGICAL CHEMISTRY, 2019, 400 (02) : 171 - 180
  • [29] NF-κB-Independent Role of IKKα/IKKβ in Preventing RIPK1 Kinase-Dependent Apoptotic and Necroptotic Cell Death during TNF Signaling
    Dondelinger, Yves
    Jouan-Lanhouet, Sandrine
    Divert, Tatyana
    Theatre, Emilie
    Bertin, John
    Gough, Peter J.
    Giansanti, Piero
    Heck, Albert J. R.
    Dejardin, Emmanuel
    Vandenabeele, Peter
    Bertrand, Mathieu J. M.
    MOLECULAR CELL, 2015, 60 (01) : 63 - 76
  • [30] Radiolabeling and evaluation of cyclohexyl (5-(2-acetamidobenzo[d]thiazol-6-yl)-2-methylpyridin-3-yl) carbamate (PK68), a potent inhibitor for receptor interacting protein 1 kinase (RIPK1)
    Kumata, Katsushi
    Yamasaki, Tomoteru
    Hiraishi, Atsuto
    Zhang, Yiding
    Wakizaka, Hidekatsu
    Ogawa, Masanao
    Nengaki, Nobuki
    Zhang, Ming-Rong
    NUCLEAR MEDICINE AND BIOLOGY, 2022, 108 : S113 - S113
1234