Primary choriocarcinoma of the maxillary gingival

被引:1
作者
Khanfir, A. [1 ]
Kaffel, T. [2 ]
Gouiaa, N. [3 ]
Boudawara, T. [3 ]
Abdelmoula, M. [2 ]
Frikha, M. [1 ]
机构
[1] CHU Habib Bourguiba, Serv Oncol Med, Sfax 3029, Tunisia
[2] CHU Habib Bourguiba, Serv ORL & Chirurg Maxillofaciale, Sfax 3029, Tunisia
[3] CHU Habib Bourguiba, Lab Anatomopathol, Sfax 3029, Tunisia
来源
REVUE DE STOMATOLOGIE ET DE CHIRURGIE MAXILLO-FACIALE | 2012年 / 113卷 / 05期
关键词
Choriocarcinoma; Non-gestational; Maxilla; Chemotherapy; GERM-CELL TUMORS; CANCER;
D O I
10.1016/j.stomax.2011.12.001
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Introduction. Primary non-gestational extragonadal choriocarcinomas are uncommon and their head and neck localization more exceptional. Observation. We report on a primary choriocarcinoma case of the mandibular gingivae in a 26-year-old woman who presented with pulmonary and renal metastasis. Complete response (clinical, biological and radiological) was achieved with combined chemotherapy according to APE regimen associating actinomycin, cisplatin and etoposid. The patient was free of disease 4 years after therapy completion. Discussion. Primary gingival mandibular choriocarcinoma is very rare. Clinical presentation is atypical; diagnosis is based on histopathological examination and positivity for HCG. Our case report showed high chemo-sensitivity and comparable outcome to the other localizations. (C) 2011 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:382 / 384
页数:3
相关论文
共 8 条
[1]  
Altintas A, 1995, Eur J Surg Oncol, V21, P579, DOI 10.1016/S0748-7983(95)97712-0
[2]  
APARICIO J, 1995, EUR UROL, V28, P19
[3]  
Droz J P, 1992, Rev Prat, V42, P817
[4]  
Krege S, 2008, EUR UROL, V53, P497, DOI 10.1016/j.eururo.2007.12.025
[5]   Rare incidence of three consecutive primary tumors in the maxillofacial region:: Retinoblastoma, leiomyosarcoma, and choriocarcinoma:: Case report [J].
Márta, U ;
Zsuzsanna, S ;
József, B ;
Zsolt, N ;
Béla, S ;
György, S .
JOURNAL OF CRANIOFACIAL SURGERY, 2001, 12 (05) :464-468
[6]   CURRENT ISSUES IN THE HISTOPATHOLOGY OF GESTATIONAL TROPHOBLASTIC TUMORS [J].
Sebire, N. J. ;
Lindsay, Iain .
FETAL AND PEDIATRIC PATHOLOGY, 2010, 29 (01) :30-44
[7]   Human chorionic gonadotropin in cancer [J].
Stenman, UH ;
Alfthan, H ;
Hotakainen, K .
CLINICAL BIOCHEMISTRY, 2004, 37 (07) :549-561
[8]   Spectrum of germ cell tumors: From head to toe [J].
Ueno, T ;
Tanaka, YO ;
Nagata, M ;
Tsunoda, H ;
Anno, I ;
Ishikawa, S ;
Kawai, K ;
Itai, Y .
RADIOGRAPHICS, 2004, 24 (02) :387-404