Setting properties and biocompatibility of dicalcium silicate with varying additions of tricalcium aluminate

被引:9
作者
Liu, Weining [1 ]
Chang, Jiang [1 ]
机构
[1] Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China
关键词
apatite; biocompatibility; calcium silicate cements; MTA; dicalcium silicate; tricalcium aluminate; MINERAL TRIOXIDE AGGREGATE; OSTEOBLASTIC DIFFERENTIATION; COMPOSITE CEMENT; IONIC PRODUCTS; STROMAL CELLS; BONE; CALCIUM; SURFACE; PROLIFERATION; BIOACTIVITY;
D O I
10.1177/0885328211398507
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
This study sought to prepare biphasic mixtures by adding tricalcium aluminate (Ca3Al2O6) into dicalcium silicate (Ca2SiO4) and to evaluate the effect of Ca3Al2O6 on setting properties and biocompatibility of the Ca2SiO4/Ca3Al2O6 mixtures as compared to pure Ca2SiO4. The results indicated that the addition of Ca3Al2O6 into Ca2SiO4 reduced the setting time and improved the compressive strength. Furthermore, Ca2SiO4/Ca3Al2O6 mixtures were bioactive and biocompatible, and had a stimulatory effect on the L929 cell growth when the content of Ca3Al2O6 was below 10%. Therefore, the mixtures with 10% Ca3Al2O6 produced the best compromise between setting and in vitro biological properties.
引用
收藏
页码:171 / 178
页数:8
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