Blood-based biomarkers of cancer-related cognitive impairment in non-central nervous system cancer: A scoping review

被引:19
作者
Oppegaard, Kate R. [1 ]
Armstrong, Terri S. [2 ]
Anguera, Joaquin A. [3 ]
Kober, Kord M. [1 ]
Kelly, Debra Lynch [4 ,5 ]
Laister, Rob C. [6 ]
Saligan, Leorey N. [7 ]
Ayala, Ana Patricia [8 ]
Kuruvilla, John [6 ]
Alm, Mark W. [9 ]
Byker, William H. [10 ]
Miaskowski, Christine [1 ,11 ]
Mayo, Samantha J. [6 ,12 ]
机构
[1] Univ Calif San Francisco, Sch Nursing, Dept Physiol Nursing, San Francisco, CA USA
[2] NCI, Neurooncol Branch, NIH, Bethesda, MD USA
[3] Univ Calif San Francisco, Dept Neurol & Psychiat, San Francisco, CA USA
[4] Univ Florida, Coll Nursing, Gainesville, FL USA
[5] Univ Florida, Hlth Canc Ctr, Gainesville, FL USA
[6] Univ Hlth Network, Princess Margaret Canc Ctr, Toronto, ON, Canada
[7] NIH, Symptoms Biol Unit, Div Intramural Res, Bethesda, MD USA
[8] Univ Toronto, Gerstein Sci Informat Ctr, Toronto, ON, Canada
[9] Toronto Gen Hosp, Univ Hlth Network, Toronto, ON, Canada
[10] Vancouver Gen Hosp, Vancouver Coastal Hlth, Vancouver, BC, Canada
[11] Univ Calif San Francisco, Sch Med, Dept Anesthesia & Perioperat Care, San Francisco, CA USA
[12] Univ Toronto, Lawrence S Bloomberg Fac Nursing, Toronto, ON, Canada
基金
美国国家卫生研究院;
关键词
Biomarkers; Cancer; Cancer-related cognitive impairment; Chemotherapy-related cognitive impairment; Cytokines; Scoping review; QUALITY-OF-LIFE; REPORTED ATTENTIONAL FUNCTION; BREAST-CANCER; TNF-ALPHA; NEUROPSYCHOLOGICAL PERFORMANCE; ADJUVANT CHEMOTHERAPY; PROMOTER POLYMORPHISM; INFLAMMATORY MARKERS; BIOSIMILAR EPOETIN; COLORECTAL-CANCER;
D O I
10.1016/j.critrevonc.2022.103822
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
This scoping review was designed to synthesize the extant literature on associations between subjective and/or objective measures of cancer-related cognitive impairment (CRCI) and blood-based biomarkers in adults with non-central nervous system cancers. The literature search was done for studies published from the start of each database searched (i.e., MEDLINE, Embase, PsycINFO, Cumulative Index to Nursing and Allied Health Literature, Cochrane Central Register of Controlled Trials, grey literature) through to October 20, 2021. A total of 95 studies are included in this review. Of note, a wide variety of biomarkers were evaluated. Most studies evaluated patients with breast cancer. A variety of cognitive assessment measures were used. The most consistent significant findings were with various subjective and objective measures of CRCI and levels of interleukin-6 and tumor necrosis factor. Overall, biomarker research is in an exploratory phase. However, this review synthesizes findings and proposes directions for future research.
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收藏
页数:18
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