TOMOGRAPHIC AND ANGIOGRAPHIC CHARACTERISTICS OF EYES WITH MACULAR FOCAL CHOROIDAL EXCAVATION

被引:66
作者
Obata, Ryo [1 ]
Takahashi, Hidenori [1 ]
Ueta, Takashi [1 ]
Yuda, Kentaro [1 ]
Kure, Kayo [1 ]
Yanagi, Yasuo [1 ]
机构
[1] Univ Tokyo, Sch Med, Dept Ophthalmol, Tokyo 1138655, Japan
来源
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES | 2013年 / 33卷 / 06期
关键词
focal choroidal excavation; optical coherence tomography; fluorescein angiography; indocyanine green angiography; fundus autofluorescent imaging; central serous chorioretinopathy; CENTRAL SEROUS CHORIORETINOPATHY; OPTICAL COHERENCE TOMOGRAPHY; INDOCYANINE GREEN VIDEOANGIOGRAPHY; THICKNESS;
D O I
10.1097/IAE.0b013e31827b6452
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: To describe detailed clinical features of eyes with focal choroidal excavation. Methods: Twenty-one eyes of 17 patients with focal choroidal excavation were retrospectively studied. All eyes underwent thorough examination including funduscopy, visual field analysis, fundus autofluorescence imaging, fluorescein angiography, indocyanine green angiography, and B-scan ultrasonography. Results: Patients' age ranged between 25 years and 70 years. Four patients (24%) were affected bilaterally. Spherical equivalent of refractive error ranged from 0.5 diopters to -10.0 diopters (D). Funduscopic examination showed hypopigmentation (n = 12) and yellowish plaquelike appearances (n = 2). Indocyanine green angiography showed not only filling defects at the excavation (n = 16) but also choroidal vascular hyperpermeability (n = 7) and punctate hyperfluorescent spots (n = 7). Cicatrized subretinal neovascularization was seen in three eyes. The mean follow-up period was 37 months (6-66 months). There was no change in the appearance of excavation. Central serous chorioretinopathy (n = 1) and choroidal neovascularization (n = 1) developed during follow-up. Conclusion: Background factors and ophthalmic findings are similar to those that have been reported previously, including relatively stable findings even after a long observation and the occurrence of central serous chorioretinopathy and choroidal neovascularization. Bilateral cases are not rare in the current cohort, and choroidal vascular hyperpermeability is frequently observed in indocyanine green angiography, suggesting there were choroidal hemodynamic changes around the excavation.
引用
收藏
页码:1201 / 1210
页数:10
相关论文
共 19 条
[1]  
Abe Sachi, 2010, Retin Cases Brief Rep, V4, P373, DOI 10.1097/ICB.0b013e3181babe7e
[2]   Reproducibility of Choroidal Thickness Measurements Across Three Spectral Domain Optical Coherence Tomography Systems [J].
Branchini, Lauren ;
Regatieri, Caio V. ;
Flores-Moreno, Ignacio ;
Baumann, Bernhard ;
Fujimoto, James G. ;
Duker, Jay S. .
OPHTHALMOLOGY, 2012, 119 (01) :119-123
[3]   Enhanced depth imaging spectral-domain optical coherence tomography of subfoveal choroidal thickness in normal Japanese eyes [J].
Fujiwara, Atsushi ;
Shiragami, Chieko ;
Shirakata, Yukari ;
Manabe, Saki ;
Izumibata, Saeko ;
Shiraga, Fumio .
JAPANESE JOURNAL OF OPHTHALMOLOGY, 2012, 56 (03) :230-235
[4]   Enhanced Depth Imaging Optical Coherence Tomography of the Choroid in Highly Myopic Eyes [J].
Fujiwara, Takamitsu ;
Imamura, Yutaka ;
Margolis, Ron ;
Slakter, Jason S. ;
Spaide, Richard F. .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 2009, 148 (03) :445-450
[5]   Torpedo maculopathy [J].
Golchet, Pamela R. ;
Jampol, Lee M. ;
Mathura, Jeevan R., Jr. ;
Daily, Mark J. .
BRITISH JOURNAL OF OPHTHALMOLOGY, 2010, 94 (03) :302-306
[6]   DIGITAL INDOCYANINE GREEN VIDEOANGIOGRAPHY OF CENTRAL SEROUS CHORIORETINOPATHY [J].
GUYER, DR ;
YANNUZZI, LA ;
SLAKTER, JS ;
SORENSON, JA ;
HO, A ;
ORLOCK, D .
ARCHIVES OF OPHTHALMOLOGY, 1994, 112 (08) :1057-1062
[7]   Optical coherence tomography findings in acute retinal pigment epitheliitis [J].
Hsu, Jason ;
Fineman, Mitchell S. ;
Kaiser, Richard S. .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 2007, 143 (01) :163-165
[8]   Persistent and bilateral choroidal vascular abnormalities in central serous chorioretinopathy [J].
Iida, T ;
Kishi, S ;
Hagimura, N ;
Shimizu, K .
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 1999, 19 (06) :508-512
[9]   Diagnostic and therapeutic challenges [J].
Jampol, Lee M. ;
Shankle, Jonathan ;
Schroeder, Robert ;
Tornambe, Paul ;
Spaide, Richard F. ;
Hee, Michael R. .
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 2006, 26 (09) :1072-1076
[10]   Two Cases of Focal Choroidal Excavation Detected by Spectral-Domain Optical Coherence Tomography [J].
Katome, Takashi ;
Mitamura, Yoshinori ;
Hotta, Fumika ;
Niki, Masanori ;
Naito, Takeshi .
CASE REPORTS IN OPHTHALMOLOGY, 2012, 3 (01) :96-103