Sildenafil-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms:Case report with review

被引：2
作者：
Gupta, Sunil K. [1 ]
Sushantika, Sushantika [1 ]
Abdelmaksoud, Ayman [2 ]
机构：
[1] All India Inst Med Sci, Dept Dermatol, Gorakhpur, Uttar Pradesh, India
[2] Venereol & Leprol Hosp, Mansoura Dermatol, Mansoura, Egypt
来源：
DERMATOLOGIC THERAPY | 2020年 / 33卷 / 06期
关键词：
drug reaction; inflammatory disorders; pharmacology; pruritus; therapysystemic; ERECTILE DYSFUNCTION; DRESS SYNDROME; DRUG ERUPTION;
D O I：
10.1111/dth.13826
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Sildenafil is one of the commonest over the counter drugs which is orally taken by the people for sexual enhancement. It is an inhibitor of phosphodiesterase type 5 (PDE5) and results in engorgement of carpora cavernosa and help in erectile dysfunction. There are fewer adverse cutaneous drug reactions reported by sildenafil perhaps due to use of the drug without medical prescription. Here we are reporting a case of sildenafil induced hypersensitivity syndrome that is possibly the first one and reviewing the medical literature on type of adverse cutaneous drug eruption due to sildenafil and other PDE5 inhibitors.
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