Surface Enhanced Raman Scattering in Surgery and Forensics

被引:0
作者
Micsa, Catalin [1 ]
Rizea, Constantin [2 ]
Rusu, Madalin Ion [3 ]
Becherescu-Barbu, Nicolae Dan [4 ]
Munteanu, Raluca [1 ]
Udrea, Mircea Virgil [4 ]
Chiricuta, Bogdan [4 ]
Parau, Anca [3 ]
Tonetto, Alain [5 ]
Notonier, Roger [5 ]
Birtoiu, Ioan Alin [1 ]
Grigorescu, Cristiana-Eugenia-Ana [3 ]
机构
[1] Univ Agron Sci & Vet Med, Fac Vet Med, Bucharest, Romania
[2] ROXY Vet SRL, Varteju Magurele, Romania
[3] Natl Inst Res & Dev Optoelect INOE 2000, POB MG-5, Magurele 77125, Jud Ilfov, Romania
[4] APEL LASER SRL, Bucharest, Romania
[5] Aix Marseille Univ, PRATIM, Site St Charles, Marseille, France
来源
2016 18TH INTERNATIONAL CONFERENCE ON TRANSPARENT OPTICAL NETWORKS (ICTON) | 2016年
关键词
surface enhanced Raman scattering; Raman laser excitation in the visible; surface plasmon; gold and silver nano-coatings; oncologic surgery diagnostic; forensics; SERS; SPECTROSCOPY; BLOOD; FDTD;
D O I
暂无
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
This paper shows some results of our work on the use of Surface Enhanced Raman Scattering as an ex vivo and in vivo diagnostic means in veterinary surgery and oncology. Also, as part of the involved research, interspecies discrimination of adipose constituents and body fluids is illustrated. These later outcomes would supply efficient instruments to forensics. An innovative system based on surface enhanced Raman scattering, primarily used in small animal surgery, will add to the ongoing research on tumour margin assessment. Samples from animal patients following therapeutic mastectomy have been investigated ex vivo using a LABRAM HR 800 microRaman spectrometer. Spectra were collected from 100 cm(-1) to 4000 cm(-1) using a 632 nm HeNe laser, which to date has been reported on in vitro human samples only. A surface enhanced Raman effect of up to 107 has been obtained on areas of surgery instruments either raw or coated with silver or gold. This dramatically improves spectral resolution and reduces the accumulation time down to 60 s, which would allow for real time diagnostic.
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