SAWYER, B. J., R. H. MORTON, C. J. WOMACK, and G. A. GAESSER. VO2max May Not Be Reached during Exercise to Exhaustion above Critical Power. Med. Sci. Sports Exerc., Vol. 44, No. 8, pp. 1533-1538, 2012. Purpose: This study was designed to determine whether VO2 reaches a maximum, equivalent to that attained in an incremental exercise test to exhaustion, during "submaximal'' fatigue-inducing constant-power exercise bouts above critical power (CP). Methods: Nine males (age = 24.6 +/- 3.6 yr, height = 182.8 +/- 6.9 cm, weight = 77.8 +/- 12.1 kg) and four females (age = 29.0 +/- 7.3 yr, height = 170.8 +/- 3.2 cm, weight = 61.8 +/- 8.2 kg) underwent an incremental VO2max test (IET) on a cycle ergometer, followed by four or five randomly assigned constant-power exercise bouts to exhaustion, on separate days. The CP for each subject was estimated using linear and nonlinear regression. Results: IET VO2max averaged 3.55 +/- 0.92 L.min(-1) (RER = 1.21 +/- 0.05, HR = 186 +/- 10 bpm, 96.1% +/- 6.3% of age-predicted maximum). Mean peak VO2 (range = 3.32 +/- 0.88 to 3.54 +/- 0.91 L.min(-1)) during the three highest constant-power bouts (two of which were 53 to 82 W less than peak power output attained during IET) was not significantly different from IET VO2max. Eleven of 13 subjects exceeded their IET VO2max during at least one of the constant-power exercise bouts. However, peak VO2 (3.11 +/- 0.79 L.min(-1)) during the lowest constant-power exercise bout, which ranged from 10 to 36 W above CP estimated with a two-parameter nonlinear model, was significantly lower than IET VO2max (88.2% +/- 9.4% of IET VO2max). Conclusions: At power outputs above CP, VO2 does not necessarily increase to maximum during constant-power exercise to exhaustion. In addition, the highest VO2 values measured during a traditional VO2 "max'' test (i.e., IET) may not reflect the highest attainable VO2 despite VO2max criteria being met.