Cefepime Neurotoxicity in a Patient With Acute Tubular Necrosis

被引：3

作者：

Ojha, Niranjan ^{[1
]}

Riaz, Sana ^{[1
]}

Eranki, Ambika ^{[2
]}

机构：

[1] SUNY Upstate Med Univ, Internal Med, Syracuse, NY 13210 USA

[2] SUNY Syracuse, Infect Dis, Syracuse, NY USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2020年 / 12卷 / 08期

关键词：

cefepime; neurotoxicity; elderly; renal impairment; nephrotoxic drugs; acute tubular necrosis;

D O I：

10.7759/cureus.9911

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Neurotoxicity is a rare side effect of Cefepime use. Cefepime can cross the blood-brain barrier and can be neurotoxic by competitive albeit weak antagonism of the gamma-aminobutyric acid complex. It is cleared by the kidneys which puts individuals with renal impairment at risk of side effects. We describe a case of Cefepime neurotoxicity in the context of nephrotoxicity secondary to the use of other drugs.

引用

页数：6

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