Patterns of tobacco-related mortality among individuals diagnosed with schizophrenia, bipolar disorder, or depression

被引:181
作者
Callaghan, Russell C. [1 ,2 ,3 ]
Veldhuizen, Scott [2 ,6 ]
Jeysingh, Trincy [2 ,5 ]
Orlan, Chloe [2 ,7 ]
Graham, Candida [1 ]
Kakouris, Gwen [2 ,4 ]
Remington, Gary [2 ]
Gatley, Jodi [2 ,8 ]
机构
[1] Univ No British Columbia, Northern Med Program, Prince George, BC V2N 4Z9, Canada
[2] Ctr Addict & Mental Hlth, Toronto, ON M5S 2S1, Canada
[3] Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON M5T 3M7, Canada
[4] Univ Toronto, Dept Psychol, Toronto, ON M1C 1A4, Canada
[5] Saba Univ, Sch Med, The Bottom, Saba, Netherlands
[6] Brock Univ, St Catharines, ON L2S 3A1, Canada
[7] Univ Western Ontario, London, ON N6A 3K7, Canada
[8] Univ Toronto, Dept Biol Sci, Toronto, ON M1C 1A4, Canada
关键词
Schizophrenia; Depression; Bipolar disorder; Standardized mortality rates; Tobacco-related conditions; MENTAL-ILLNESS; SMOKING-CESSATION; EXCESS MORTALITY; CARDIOVASCULAR MORBIDITY; CANCER-MORTALITY; PSYCHIATRIC-DISORDERS; 1ST-DEGREE RELATIVES; ADMINISTRATIVE DATA; HOSPITAL DISCHARGE; PHYSICAL ILLNESS;
D O I
10.1016/j.jpsychires.2013.09.014
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Even though individuals with psychiatric conditions have a prevalence of smoking approximately 2-4 times greater than the general population, surprisingly little evidence exists to inform an assessment of the full range of tobacco-related mortality in such populations. The current study aims to provide mortality estimates for conditions causally related to tobacco use among individuals hospitalized with a primary psychiatric diagnosis in California from 1990 to 2005. Restricting cases to those of individuals aged 35 or older at the mid-point of their follow-up period, we assembled cohorts of individuals with ICD-9 diagnoses of schizophrenia and related disorders ("schizophrenia"; n = 174,277), depressive disorders (n = 338,250), or bipolar disorder (n = 78,739). Inpatient records were linked to death-certificate data. We generated age-, sex-, and race-adjusted standardized mortality ratios (SMRs) for the 19 diseases identified by the Centers for Disease Control and Prevention as being causally linked to tobacco use. The SMRs for all tobacco-linked diseases combined were: schizophrenia, 2.45 (95% CI = 2.41-2.48); bipolar, 1.57 (95% CI = 1.53-1.62); and depression, 1.95 (95% CI = 1.93-1.98). Tobacco-related conditions comprised approximately 53% (23,620/44,469) of total deaths in the schizophrenia, 48% (6004/12,564) in the bipolar, and 50% (35,729/71,058) in the depression cohorts. Addressing tobacco use in psychiatric populations is a critical clinical and public-health concern, especially in light of the currently limited clinical attention devoted to tobacco use in these groups. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码:102 / 110
页数:9
相关论文
共 117 条
[1]  
American Medical Association, 2008, ICD 9 CM INT CLASS D
[2]  
Anderson R N, 2001, Natl Vital Stat Rep, V49, P1
[3]   Mortality of patients with mood disorders: follow-up over 34-38 years [J].
Angst, F ;
Stassen, HH ;
Clayton, PJ ;
Angst, J .
JOURNAL OF AFFECTIVE DISORDERS, 2002, 68 (2-3) :167-181
[4]  
[Anonymous], 2008, Modern epidemiology
[5]   Mortality in schizophrenia [J].
Auquier, Pascal ;
Lancon, Christophe ;
Rouillon, Frederic ;
Lader, Malcolm .
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, 2007, 16 (12) :1308-1312
[6]   Smoking cessation in severe mental illness: what works? [J].
Banham, Lindsay ;
Gilbody, Simon .
ADDICTION, 2010, 105 (07) :1176-1189
[7]   Reduced cancer incidence among patients with schizophrenia [J].
Barak, Y ;
Achiron, A ;
Mandel, M ;
Mirecki, I ;
Aizenberg, D .
CANCER, 2005, 104 (12) :2817-2821
[8]   Causes of the excess mortality of schizophrenia [J].
Brown, S ;
Inskip, H ;
Barraclough, B .
BRITISH JOURNAL OF PSYCHIATRY, 2000, 177 :212-217
[9]   Excess mortality of schizophrenia - A meta-analysis [J].
Brown, S .
BRITISH JOURNAL OF PSYCHIATRY, 1997, 171 :502-508
[10]   Twenty-five year mortality of a community cohort with schizophrenia [J].
Brown, Steve ;
Kim, Miranda ;
Mitchell, Clemence ;
Inskip, Hazel .
BRITISH JOURNAL OF PSYCHIATRY, 2010, 196 (02) :116-121