Interleukin-17 in veterinary animal species and its role in various diseases: A review

被引:18
作者
Mensikova, Marketa [1 ]
Stepanova, Hana [1 ]
Faldyna, Martin [1 ]
机构
[1] Vet Res Inst, Brno 62100, Czech Republic
关键词
Interleukin-17; Inflammation; Horse; Cattle; Swine; INFLAMMATORY AIRWAY DISEASE; MESSENGER-RNA EXPRESSION; INDUCED MATRIX-METALLOPROTEINASE; ENTERICA SEROTYPE TYPHIMURIUM; AVIUM SUBSP PARATUBERCULOSIS; PULMONARY MONONUCLEAR-CELLS; IN-VITRO EXPOSURE; GENE-EXPRESSION; T-CELLS; STAPHYLOCOCCUS-AUREUS;
D O I
10.1016/j.cyto.2013.06.002
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Interleukin 17 (IL-17) as one of the pro-inflammatory cytokines is a very important player in the immune response to many pathogens and seems to play a role also in certain chronic and autoimmune diseases. Many studies showing the importance of this cytokine were conducted on murine models and human patients. In recent years, some experiments with other animals in which interleukin-17 was measured were carried out. This review is focused on the findings that have been observed and described in important veterinary species of animals. (c) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码:11 / 17
页数:7
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